Results 131 to 140 of about 553,414 (348)

Study on Hematological and Biochemical Characters of Cloned Duroc Pigs and Their Progeny

open access: yesAnimals, 2019
To increase public understanding in cloned animals produced by somatic cell nuclear transfer technology, our previous study investigated the carcass trait and meat quality of the clones (paper accepted), and this study we further evaluate differences by ...
Ting Gu   +8 more
doaj   +1 more source

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

open access: yesAdvanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao   +10 more
wiley   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

open access: yesAdvanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu   +16 more
wiley   +1 more source

Evaluating reproductive outcomes in Saanen and Alpine doelings with suboptimal live weight and performance of their progeny

open access: yesSpanish Journal of Agricultural Research
Aim of the study: This study aimed to evaluate the reproductive performance of Saanen and Alpine doelings with suboptimum live weight and the productive performance of their progeny.
Luisa E.S. Hernández-Arteaga   +8 more
doaj   +1 more source

Modelling of selection and mating decisions in tree breeding programs [PDF]

open access: yes, 1996
Hardwood trees from the temperate forests of southern Australia are an important source of timber for high quality paper. Two species in particular, Eucalyptus globulus and Eucalyptus nitens are well suited to this purpose and are now widely grown in ...
Howlett, P., Thompson, C.
core  

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

open access: yesAdvanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang   +11 more
wiley   +1 more source

Improving Crossing Efficiency by Exploiting the Genetic Potential of Allotetraploid Cooking Bananas

open access: yesHorticulturae
Conventional breeding involves considerable genetic recombination. To maximize breeding efforts, it is necessary to increase seed yield. This study proposes to improve seed yield by using tetraploid bananas as part of a genetic improvement programme for ...
Camille Ulrich Dzokouo Dzoyem   +3 more
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Reading a Protoevangelium in the Context of Genesis [PDF]

open access: yes, 2014
This article proposes that the case for a ‘messianic’ reading of Gen. 3:15 is cumulative. No single individual argument is decisive and it is virtually impossible to sustain a robust protevangelium interpretation of this text within the context of Gen. 3
Pettus, David
core   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

open access: yesAdvanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen   +12 more
wiley   +1 more source

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