Results 181 to 190 of about 440,683 (312)

Tetraploids or polyploid giants: who is truly dangerous? [PDF]

Trends Cell Biol
Bloomfield M, Vora S, Epa D, Gabrielli B, Cimini D.   +4 more
europepmc   +1 more source

Privatization's Progeny

, 2013
Privatization’s proponents are branching out.  They’ve traditionally relied on government contracting to boost regulatory efficiency, maximize budgetary savings, enhance unitary control over the administrative state, and reap political dividends.  Now, however, these proponents are also blazing newer, bolder paths.  They’re experimenting
openaire   +2 more sources

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source

Application of optimal contribution selection, trait distribution management, and group selection in layer chickens. [PDF]

Genet Sel Evol
Wolc A, Kinghorn BP, Kinghorn AJ, Dekkers JCM.   +3 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Human TET2-Mutant Clonal Hematopoiesis Expansion Is Driven by Distinct Inflammatory Signaling Responses in Stem Cells Versus Myeloid Progeny. [PDF]

Blood Cancer Discov
Huerga Encabo H, D'Agostino G, Sturgess K, Lord AE, Jong ED, Ferrelli A, Sharma A, Mian SA, Habel K, Llorian-Sopena M, Ramesh AP, Mohamad Nor F, Foissner H, Garcia-Albornoz M, Graver L, Papazoglou D, Ngo S, Anjos-Afonso F, Ariza-McNaughton L, Ficz G, Bonnet D.   +20 more
europepmc   +1 more source

Advances and perspectives in animal models of human hepatitis A virus

Animal Models and Experimental Medicine, EarlyView.
Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li, Pei‐Yu Jiang, Hui Zhao, Cheng‐Feng Qin   +3 more
wiley   +1 more source

The invasive bark beetle, <i>Pagiocerus frontalis</i> (Fabricius): as an emerging maize storage pest in Tanzania. [PDF]

Front Plant Sci
Chidege MY, Venkataramana PB, Ndakidemi PA.   +2 more
europepmc   +1 more source

Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?

Annals of Neurology, EarlyView.
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano, Francesca Palumbo, Gabriele Mora, Salvatore Gallone, Giovanni De Marco, Ilaria Merulla, Claudia Paolantonio, Alessandra Maccabeo, Antonio Canosa, Umberto Manera, Rosario Vasta, Barbara Iazzolino, Marcella Testa, Giuseppe Fuda, Paolina Salamone, Giulia Marchese, Federico Casale, Cristina Moglia, Andrea Calvo, Giuseppe Borghero, Adriano Chiò   +20 more
wiley   +1 more source

Dissecting the homeodomain <i>MAT</i> locus and engineering novel tripolar and bipolar mating systems in <i>Cryptococcus amylolentus</i>. [PDF]

mBio
Xiong L, Yadav V, Sun S, Heitman J.
europepmc   +1 more source