Results 191 to 200 of about 440,683 (312)

Electrical Impedance Myography Detects Disease Progression over 12 to 24 Months in Facioscapulohumeral Muscular Dystrophy

Annals of Neurology, EarlyView.
Objective Targeted therapies for facioscapulohumeral muscular dystrophy (FSHD) are progressing through clinical trials. Electrical impedance myography (EIM) provides a noninvasive biomarker of muscle composition that may be valuable especially in early phase trials. This study evaluated EIM data from a multicenter FSHD cohort over 24 months.
Karlien Mul, Michael P. McDermott, Russell J. Butterfield, Bakri Elsheikh, Kate Eichinger, Nicholas E. Johnson, Doris G. Leung, Samantha LoRusso, Leann Lewis, William B. Martens, Perry B. Shieh, Leo H. Wang, Michaela Walker, Rabi Tawil, Jeffrey M. Statland, ReSolve Investigators of the FSHD‐CTRN   +15 more
wiley   +1 more source

Variation in rate of body weight gain during pregnancy in beef heifers: association with early life health events and influence on progeny performance. [PDF]

Transl Anim Sci
Cushman RA, Hauxwell KM, Caton JS, Freetly HC.   +3 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Limonene and its metabolite perillyl alcohol inhibit Chlamydia trachomatis growth by altering host isoprenoid metabolism. [PDF]

Nat Prod Bioprospect
Cebollada P, Reigada I, Ylätalo M, Gerediaga C, López V, Hanski L.   +5 more
europepmc   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Microglial Lyn Kinase-TRPV4 axis mediates social deficits in a maternal immune activation model. [PDF]

J Neuroinflammation
Islam R, Zhang F, Choudhary HH, Yoshida J, Thomas AJ, Sorum B, Hanafy KA.   +6 more
europepmc   +1 more source

Short‐Term Scheduling Optimization of a Single‐Pipeline Refining System With High Melting Point Crude Oil

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In order to reflect the actual production situation more comprehensively and optimize the production cost, this paper solves the short‐term scheduling optimization problem for a single pipeline containing high melting point crude oil. Based on the refining plan given by the upper layer, a multi‐objective optimization model with high melting ...
Jing Yao, Xianxin Liu, Zhen Pan, Chengming Hao, Xiangwei Xu, Wei Jia   +5 more
wiley   +1 more source

Virus-mediated, heritable gene editing in groundcherry (<i>Physalis grisea</i>). [PDF]

Front Plant Sci
Tibebu R, Ellison EE, Winecke SR, Prichard LE, Klejeski N, Donahue LI, Cody JP, Baysal C, Starker CG, Van Eck J, Voytas DF.   +10 more
europepmc   +1 more source

Optimizing Structural Parameters of a Water Distribution Device in Cylindrical High‐Flowrate Mixed Bed Using Multiobjective Genetic Algorithm

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT High‐flowrate mixed bed is the foremost desalination equipment in the condensate polishing system. The water distribution device determining the water distribution uniformity directly affects its operation stability, output water quality, and service life of the resins.
Jing Zhu, Yuhan Liu, Kai Tuo, Xiaohong Zhang, Zhe Xia, Zhao Wang   +5 more
wiley   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

The Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga, Verônica Oliveira‐Bahia, Maria Auxiliadora Ferreira, José Ribamar Felipe Marques, Diva Araújo Guimarães   +4 more
wiley   +1 more source