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Decreased DNA density is a better indicator of a nuclear bleb than lamin B loss.
J Cell SciBunner S +26 more
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Pediatrics, 1956
A typical case of progeria (Hutchinson-Gilford syndrome) is reported including the findings of the necropsy. Death occurred at the age of 11 years as the result of an accident. Analysis of cephalometric roentgenograms of this patient revealed that the characteristic facies of progeria results from marked retardation of facial growth in the presence of ...
Ira M. Rosenthal +4 more
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A typical case of progeria (Hutchinson-Gilford syndrome) is reported including the findings of the necropsy. Death occurred at the age of 11 years as the result of an accident. Analysis of cephalometric roentgenograms of this patient revealed that the characteristic facies of progeria results from marked retardation of facial growth in the presence of ...
Ira M. Rosenthal +4 more
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Archives of Dermatology, 1989
Progeria, also known as the Hutchinson-Gilford syndrome, is an extremely rare condition that was initially reported by Johnathan Hutchinson in 1886 and further described by Hastings Gilford in 1904. Transmission is most likely from a sporadic autosomal dominant mutation.
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Progeria, also known as the Hutchinson-Gilford syndrome, is an extremely rare condition that was initially reported by Johnathan Hutchinson in 1886 and further described by Hastings Gilford in 1904. Transmission is most likely from a sporadic autosomal dominant mutation.
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Journal of Anti-Aging Medicine, 2003
Abstract In a book on cell senescence in human disease, it is negligent not to discuss progerias, yet from what perspective? Does cell senescence cause progerias? Do the progerias cause cell senescence? Are “progcroid syndromes” (Brown, 1995) related to cell senescence at all (Greally et al., 1992)?
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Abstract In a book on cell senescence in human disease, it is negligent not to discuss progerias, yet from what perspective? Does cell senescence cause progerias? Do the progerias cause cell senescence? Are “progcroid syndromes” (Brown, 1995) related to cell senescence at all (Greally et al., 1992)?
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American Journal of Diseases of Children, 1940
The term progeria, meaning prematurely old, was first given to a rare disease of childhood by Hastings Gilford.1The original case was described by Hutchinson,2but Gilford classified the disease as a distinct clinical entity and presented 2 cases of his own, in one of which the patient eventually came to autopsy The children all had many similar ...
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The term progeria, meaning prematurely old, was first given to a rare disease of childhood by Hastings Gilford.1The original case was described by Hutchinson,2but Gilford classified the disease as a distinct clinical entity and presented 2 cases of his own, in one of which the patient eventually came to autopsy The children all had many similar ...
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American Journal of Diseases of Children, 1945
As aptly stated forty years ago, 1 children suffering from progeria present a unique and weird clinical picture of "immaturity upon which has descended the blight of premature senility." This disease, which first becomes manifest at approximately 1 year of age in a previously healthy infant, is characterized by dwarfism, by a loss of hair and of ...
NATHAN B. TALBOT +4 more
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As aptly stated forty years ago, 1 children suffering from progeria present a unique and weird clinical picture of "immaturity upon which has descended the blight of premature senility." This disease, which first becomes manifest at approximately 1 year of age in a previously healthy infant, is characterized by dwarfism, by a loss of hair and of ...
NATHAN B. TALBOT +4 more
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American Journal of Diseases of Children, 1929
The name "progeria" (prematurely old) was first applied by Hastings Gilford 1 to describe an unusual morbid condition in which there existed a combination of senility and infantilism. Three cases were reported, two of which had previously been presented before the Royal Society of Medicine and Surgery in London, the first by Jonathan Hutchinson, 2 in ...
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The name "progeria" (prematurely old) was first applied by Hastings Gilford 1 to describe an unusual morbid condition in which there existed a combination of senility and infantilism. Three cases were reported, two of which had previously been presented before the Royal Society of Medicine and Surgery in London, the first by Jonathan Hutchinson, 2 in ...
openaire +1 more source