Results 251 to 260 of about 17,639 (297)

Inflammation and Fibrosis in Progeria: Organ-Specific Responses in an HGPS Mouse Model. [PDF]

Int J Mol Sci
Krüger P, Schroll M, Fenzl F, Lederer EM, Hartinger R, Arnold R, Cagla Togan D, Guo R, Liu S, Petry A, Görlach A, Djabali K.   +11 more
europepmc   +1 more source

Inhibition of poly(ADP-Ribosyl)ation reduced vascular smooth muscle cells loss and improves aortic disease in a mouse model of human accelerated aging syndrome. [PDF]

Cell Death Dis
Cardoso D, Guilbert S, Guigue P, Carabalona A, Harhouri K, Peccate C, Tournois J, Guesmia Z, Ferreira L, Bartoli C, Levy N, Colleaux L, Nissan X, Muchir A.   +13 more
europepmc   +1 more source

Unveiling the potential impact of RNA m5C methyltransferases NSUN2 and NSUN6 on cellular aging. [PDF]

Front Genet
Zhou J, Han Y, Ji F, Zhang R, Liang Y, Zhao X, Hou R.   +6 more
europepmc   +1 more source

The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway. [PDF]

Geroscience
Monterrubio-Ledezma F, Salcido-Gómez A, Zavaleta-Vásquez T, Navarro-García F, Cisneros B, Massieu L.   +5 more
europepmc   +1 more source

Restoring functional TDP-43 oligomers in ALS and laminopathic cellular models through baicalein-induced reconfiguration of TDP-43 aggregates. [PDF]

Sci Rep
Chang HY, Wang IF.
europepmc   +1 more source

Cardiac and skeletal muscle manifestations in the G608G mouse model of Hutchinson-Gilford progeria syndrome. [PDF]

Aging Cell
Hong Y, Rannou A, Manriquez N, Antich J, Liu W, Fournier M, Omidfar A, Rogers RG.   +7 more
europepmc   +1 more source

Endothelial cell-specific progerin expression does not cause cardiovascular alterations and premature death. [PDF]

Aging Cell
Benedicto I, Hamczyk MR, Nevado RM, Barettino A, Carmona RM, Espinós-Estévez C, Gonzalo P, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Dorado B, Andrés V.   +11 more
europepmc   +1 more source

Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells. [PDF]

Proc Natl Acad Sci U S A
Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V.   +13 more
europepmc   +1 more source