Results 121 to 130 of about 551,564 (339)

Effectiveness of high‐dose transvaginal progesterone supplementation for women who are undergoing a frozen‐thawed embryo transfer

Reproductive Medicine and Biology, 2018
Purpose To evaluate the effectiveness of high‐dose progesterone supplementation for women who are undergoing a frozen‐thawed embryo transfer (FET). Methods Among the 2010 FET cycles that were included in the present study, 1188 were 1200 mg/d of vaginal ...
Yihsien Enatsu, Noritoshi Enatsu, Kanako Kishi, Toshiro Iwasaki, Yukiko Matsumoto, Shoji Kokeguchi, Masahide Shiotani   +6 more
doaj   +1 more source

Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis

, 2022
Ashley S. Cloud, Faezeh Koohestani, Michelle M. McWilliams, Sornakala Ganeshkumar, Sumedha Gunewardena, Amanda Graham, Warren B. Nothnick, Vargheese M. Chennathukuzhi   +7 more
openalex   +2 more sources

Predicting MammaPrint Recurrence Risk from Breast Cancer Pathological Images Using a Weakly Supervised Transformer

Advanced Science, EarlyView.
This study presents CPMP, a weakly supervised transformer model that predicts MammaPrint recurrence risk directly from routine histopathological images of early‐stage HR+/HER2− breast cancer patients. CPMP enables spatial heatmap visualization, analysis of cellular‐level interaction patterns, and an in‐depth characterization of morphological phenotypes
Chaoyang Yan, Linwei Li, Xiaolong Qian, Yang Ou, Zhidong Huang, Zhihan Ruan, Wenting Xiang, Hong Liu, Jian Liu   +8 more
wiley   +1 more source

Serum progesterone distribution in normal pregnancies compared to pregnancies complicated by threatened miscarriage from 5 to 13 weeks gestation: a prospective cohort study

BMC Pregnancy and Childbirth, 2018
Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the distribution of maternal serum progesterone in normal pregnancies compared to ...
Chee Wai Ku, John C. Allen Jr, Sze Min Lek, Ming Li Chia, Nguan Soon Tan, Thiam Chye Tan   +5 more
doaj   +1 more source

TGF beta 1 attenuates expression of prolactin and IGFBP-1 in decidualized endometrial stromal cells by both SMAD-dependent and SMAD-independent pathways [PDF]

, 2010
Background: Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation.
Brosens, Jan J., Critchley, Hilary O. D., Dey, Sudhansu Kumar, Jones, Marius, Kane, Nicole M., Kelly, Rodney W., Saunders, Philippa T. K.   +6 more
core   +4 more sources

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

Divergent behavior of cyclin E and its low molecular weight isoforms to progesterone-induced growth inhibition in MCF-7 cells

Advanced Biomedical Research, 2015
Background: Progesterone is a steroid hormone that modulates proliferation and differentiation in a cell phase and tissue-specific manner. Its function in breast cancer cells is of great significance since it can predict susceptibility of tumor cells to ...
Hamed Montazeri, Saeid Bouzari, Kayhan Azadmanesh, Seyed Nasser Ostad, Mohammad Hossein Ghahremani   +4 more
doaj   +1 more source

Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]

, 2016
ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S., Kalhor, H.R., Tabarraei, A.   +2 more
core   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

The impact of late follicular progesterone level on in vitro fertilization-intracytoplasmic sperm injection outcome: Case-control study

International Journal of Reproductive BioMedicine, 2020
Background: Studies have been conducted to improve the pregnancy rate through the in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) program.
Diana Novia, Hilma Putri Lubis, Binarwan Halim, Anantya Pustimbara, Retno Lestari, Abinawanto Abinawanto, Anom Bowolaksono   +6 more
doaj   +1 more source