Results 101 to 110 of about 536,566 (348)
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
The impact of micronized progesterone on the endometrium: a systematic review
Climacteric, 2016 Postmenopausal women with an intact uterus using estrogen therapy should receive a progestogen for endometrial protection. International guidelines on menopausal hormone therapy (MHT) do not specify on progestogen type, dosage, route of application and ...
P. Stute, J. Neulen, L. Wildt
semanticscholar +1 more source
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Middle East Fertility Society Journal, 2012 Objectives: To compare vaginal with intramuscular progesterone administration to prevent preterm labor and to detect the effect of both on the uterine and fetal circulations. Study design: Prospective comparative clinical trial.
Azza A. Abd El Hameed
doaj +1 more source
Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]
, 2020 In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia +3 more
core +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
Advanced Science, EarlyView.We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
Reproductive Medicine and Biology, 2018 Purpose To evaluate the effectiveness of high‐dose progesterone supplementation for women who are undergoing a frozen‐thawed embryo transfer (FET). Methods Among the 2010 FET cycles that were included in the present study, 1188 were 1200 mg/d of vaginal ...
Yihsien Enatsu +6 more
doaj +1 more source
The effect of exogenous glucose infusion on early embryonic development in lactating dairy cows [PDF]
, 2018 peer-reviewedThe objective of this study was to examine the effect of intravenous infusion of glucose on early embryonic development in lactating dairy cows. Nonpregnant, lactating dairy cows (n = 12) were enrolled in the study (276 ± 17 d in milk). On d
Butler, Stephen +9 more
core +2 more sources
Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Stress-induced increases in progesterone and cortisol in naturally cycling women
Neurobiology of Stress, 2016 Studies with animals of both sexes show that the adrenal glands release progesterone in addition to cortisol in response to stress. However, little is known about the progesterone response to stress in naturally cycling women.
A. Y. Herrera, S. Nielsen, M. Mather
semanticscholar +1 more source