Results 81 to 90 of about 413,118 (356)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Progesterone receptors in the human placenta: Expression, signalling characteristics and functional relevance [PDF]

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The human placenta is a transient life sustaining organ which is responsible for mediating all the physiological exchanges between the mother and the fetus.
Zachariades, Elena
core  

Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats [PDF]

, 2010
Heba F SalemFaculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptAbstract: The production of an intramuscular (IM) injection of natural progesterone would provide a safer solution than using semi synthetic progesterone.
null Salem, Heba F Salem
core   +2 more sources

Comparison of the efficacy of vaginal micronised progesterone tablet and gel for in vitro fertilisation

Journal of Obstetrics and Gynaecology
Background Luteal phase support (LPS) with progesterone is a generally accepted practice after controlled ovarian stimulation, although the best protocols for LPS have been debated.
Soo Jin Han, Hoon Kim, Yun Soo Hong, Sung Woo Kim, Seung-Yup Ku, Chang Suk Suh   +5 more
doaj   +1 more source

Inter-assay variation and reproducibility of progesterone measurements during ovarian stimulation for IVF. [PDF]

PLoS ONE, 2018
In recent years there is increasing evidence that elevated progesterone levels during ovarian stimulation for IVF / ICSI have a negative impact on the ART-outcome.
Barbara Lawrenz, Junard Sibal, Nicolas Garrido, Emmanuel Abu, Alliza Jean, Laura Melado, Human M Fatemi   +6 more
doaj   +1 more source

Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes* [PDF]

Endocrinology, 2000
For rat pituitary cells, progesterone receptor (PR) protein localizes to gonadotropes and PR messenger RNA is induced by E2 and rapidly but transiently down-regulated by progesterone. Here we quantitatively establish the down-regulatory effect of progesterone on PR protein and evaluate possible mechanisms.
J L, Turgeon, D W, Waring
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Specific Association between Facial Disgust Recognition and Estradiol Levels in Naturally Cycling Women. [PDF]

, 2015
Subtle changes in social cognition are associated with naturalistic fluctuations in estrogens and progesterone over the course of the menstrual cycle.
H. Valerie Curran (724366), Sunjeev K. Kamboj (724364), H Valerie Curran, Kathleen M. Krol (724365), Curran, H., Kathleen M Krol, Curran H. Valerie, Krol, KM, Curran, HV, Krol, K., Kamboj Sunjeev K., Kamboj, SK, Kamboj, S., Krol Kathleen M., Sunjeev K Kamboj   +14 more
core   +1 more source

Does pretrigger echogenic endometrium in assisted reproductive technology cycles reflect raised serum progesterone level?

Journal of Human Reproductive Sciences, 2018
Background: Serum progesterone is the main hormone of the luteal phase. The hyperechoic pattern of the endometrium in the luteal phase is believed to be induced by raised serum progesterone.
Monna Pandurangi, N Sanjeeva Reddy, G Usha Rani, Hepzibha Kirubamani   +3 more
doaj   +1 more source

Molecular evidence of functional progesterone withdrawal in human myometrium

Nature Communications, 2016
Progesterone suppresses uterine contractility acting through its receptors (PRA/B). The mechanism by which human labour is initiated in the presence of elevated circulating progesterone has remained an enigma since Csapo first theorized of a functional ...
Lubna Nadeem, O. Shynlova, E. Matysiak-Zablocki, S. Mesiano, Xuesen Dong, S. Lye   +5 more
semanticscholar   +1 more source