Results 71 to 80 of about 403,170 (356)

Does pretrigger echogenic endometrium in assisted reproductive technology cycles reflect raised serum progesterone level?

Journal of Human Reproductive Sciences, 2018
Background: Serum progesterone is the main hormone of the luteal phase. The hyperechoic pattern of the endometrium in the luteal phase is believed to be induced by raised serum progesterone.
Monna Pandurangi, N Sanjeeva Reddy, G Usha Rani, Hepzibha Kirubamani   +3 more
doaj   +1 more source

Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices

Advanced Materials Technologies, EarlyView.
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen, Cong Minh Nguyen, Quang Thang Trinh, Minh Anh Huynh, Khanh Vinh Ho, Dang Co Pham, Dzung Dao, Sven Ingebrandt, Sina Jamali, Xuan Thang Vu, Nam‐Trung Nguyen, Tuan‐Khoa Nguyen   +11 more
wiley   +1 more source

Progesterone and neurology

Gynecological Endocrinology, 1999
Neurological diseases are frequently observed in perimenopausal women and can be characterized by their gender-specific occurrence. These observations raise the question whether sex steroids are also involved in neurological diseases. Epidemiological data have shown that in Austria in 1993, the prescription rate of psychotropics, hypnotics, and ...
D M, Gruber, M O, Sator, F, Wieser, C, Worda, J C, Huber   +4 more
openaire   +2 more sources

Molecular evidence of functional progesterone withdrawal in human myometrium

Nature Communications, 2016
Progesterone suppresses uterine contractility acting through its receptors (PRA/B). The mechanism by which human labour is initiated in the presence of elevated circulating progesterone has remained an enigma since Csapo first theorized of a functional ...
Lubna Nadeem, O. Shynlova, E. Matysiak-Zablocki, S. Mesiano, Xuesen Dong, S. Lye   +5 more
semanticscholar   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

A questionnaire-based audit to assess overall experience and convenience among patients using vaginal progesterone tablets (Lutigest®) for luteal phase support during IVF treatment

Patient Related Outcome Measures, 2017
Polly Heine,1 Laura Sellar,1 Sue Whitten,2 Priti Bajaj2 1Fertility Team, The Agora Gyneacology and Fertility Centre, Hove, 2Medical Affairs, Ferring Pharmaceuticals, West Drayton, UK Purpose: The aim of this audit was to assess the overall experience and
Heine P, Sellar L, Whitten S, Bajaj P
doaj  

Vaginal versus intramuscular progesterone in the prevention of preterm labor and their effect on uterine and fetal blood flow

Middle East Fertility Society Journal, 2012
Objectives: To compare vaginal with intramuscular progesterone administration to prevent preterm labor and to detect the effect of both on the uterine and fetal circulations. Study design: Prospective comparative clinical trial.
Azza A. Abd El Hameed
doaj   +1 more source

Fatostatin reverses progesterone resistance by inhibiting the SREBP1-NF-κB pathway in endometrial carcinoma

Cell Death and Disease, 2021
Progesterone resistance can significantly restrict the efficacy of conservative treatment for patients with endometrial cancer who wish to preserve their fertility or those who suffer from advanced and recurrent cancer.
Xiaohong Ma, Tianyi Zhao, Hong Yan, Kui Guo, Zhiming Liu, Lina Wei, Wei Lu, Chunping Qiu, Jie Jiang   +8 more
doaj   +1 more source

Progesterone for premenstrual syndrome [PDF]

Cochrane Database of Systematic Reviews, 2006
Premenstrual Syndrome (PMS) is the term for severe symptoms experienced by about 5% of menstruating women up to two weeks before their menstrual periods, but not at other times. Treatment with progesterone may restore a deficiency, or balance the level of progesterone with other menstrual hormones. Progesterone therapy may reduce the effects of falling
Ford, O., Lethaby, A., Roberts, H., Mol, B.   +3 more
openaire   +5 more sources

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source