Results 131 to 140 of about 2,874,490 (301)

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

Epilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia, Jina Babanzadeh, Marcello Scala, Lorenzo Perilli, Pasquale Striano   +4 more
wiley   +1 more source

Donkwa Enriched With Goron‐Tula (Azanza garckeana) Modulates Sexual Behavior and Activity of Enzymes Linked With Erectile Dysfunction in High‐Fat Diets/ Streptozotocin‐Induced (STZ/HFD) Diabetic Rats

Food Chemistry International, EarlyView.
(A) Mount number, (B) mount latency, (C) intromission number, and (D) intromission latency are the parameters of sexual behavior. Met = metformin. D100 = 100 Donkwa. D90G10 = 90% Donkwa + 10% Goron‐Tula. D85G15 = 85% Donkwa + 15% Goron‐Tula. D80G20 = 80% Donkwa + 20% Goron‐Tula. The mean ± standard error of the mean (SEM) expressed the results. *Values
O. T. Mamukuyomi, O. S. Ijarotimi, A. A. Badejo   +2 more
wiley   +1 more source

The genomic landscape of HER2 negative metastatic breast cancer with loss of estrogen and progesterone receptors. [PDF]

Breast
Migliaccio I, Paoli M, Biagioni C, Guarducci C, Galardi F, Anichini G, Biganzoli L, Benelli M, Malorni L.   +8 more
europepmc   +1 more source

Functional Implications of Estrogen and Progesterone Receptors Expression in Adenomyosis, Potential Targets for Endocrinological Therapy. [PDF]

J Clin Med, 2022
Sztachelska M, Ponikwicka-Tyszko D, Martínez-Rodrigo L, Bernaczyk P, Palak E, Półchłopek W, Bielawski T, Wołczyński S.   +7 more
europepmc   +1 more source

Enhancement of cell surface expression and receptor functions of membrane progestin receptor α (mPRα) by progesterone receptor membrane component 1 (PGRMC1): evidence for a role of PGRMC1 as an adaptor protein for steroid receptors.

Endocrinology, 2014
P. Thomas, Y. Pang, Jing Dong
semanticscholar   +1 more source

Value of Axillary Palpation and Ultrasound, and Axillary Recurrence in Male Breast Cancer: Results of the Registry Study

International Journal of Cancer, EarlyView.
ABSTRACT Clinical and sonographic examination of breasts and axillae is standard in breast cancer (BC) care. The aim of this study is to highlight the value of axillary ultrasound in identifying axillary recurrences in male BC, which is still little considered in the literature.
Monika Graeser, Susen Bothin, Oleg Gluz, Mathias Warm, Atanas Ignatov, Holm Eggemann   +5 more
wiley   +1 more source

A comparative in silico and in vitro analysis of antiviral agents targeting estrogen and progesterone receptors in breast cancer. [PDF]

Sci Rep
Mugundan UM, Saravanan V, Ganesan RM.
europepmc   +1 more source

Relationship of Tubule Formation, Indian File Pattern and Apocrine Change With Estrogen and Progesterone Receptors and HER2 Immunostaining. [PDF]

Cureus, 2022
Singh D, Agarwal A, Anthony ML, Paul P, Singh M, Rao S, Ravi B, Chowdhury N.   +7 more
europepmc   +1 more source

Progesterone receptors: form and function in brain.

Frontiers in neuroendocrinology (Print), 2008
R. Brinton, Richard F. Thompson, M. Foy, M. Baudry, Jun-Ming Wang, C. Finch, T. Morgan, C. Pike, W. Mack, F. Stanczyk, J. Nilsen   +10 more
semanticscholar   +1 more source

Cross‐Regulation Between DNA Methylation and Circadian Clock Reprogramming in Ovarian Cancer: Mechanistic Insights, Biomarker Potential, and Therapeutic Implications

International Journal of Cancer, EarlyView.
ABSTRACT Early diagnosis remains challenging, recurrence rates remain high, and platinum resistance frequently develops in ovarian cancer (OC), collectively representing major barriers to long‐term patient survival. DNA methylation (DNAm), as a relatively stable yet dynamically modifiable epigenetic signature, can capture alterations in tumor states ...
Min Xing, Chang Zhou, Yi Tang, Shuhui Xu, Shasha Zhou, Weiai Liu, Huiping Liu   +6 more
wiley   +1 more source