Nestorone, a potent progestin, exhibits anti-inflammatory activity and prevents preterm birth in murine models of premature labor. [PDF]
Kumar N +11 more
europepmc +1 more source
Reproductive performance of ewes treated with intravaginal progestin
Introduction; Previous research; Procedure; Initial breeding; Second breeding; Third breeding; Fourth breeding; Statistical analysis; Effect of progestin treatment and season; Synchronization of estrus; Conception rate, percentage of ewes lambing, and ...
Ruttle, J. L. (Jack Leo); Menzies, John M.
core
Fertility‐Sparing Treatment of Endometrial Cancer: Survey of Australian Practice
ABSTRACT Background Endometrial cancer is the most common gynaecological malignancy in Australia. Patients diagnosed in their reproductive window may desire a fertility‐sparing approach, opposed to standard surgical care. International guidelines on fertility‐sparing management exist; however, these highlight the lack of high‐level evidence to support ...
Harrison Odgers, Rhonda Farrell
wiley +1 more source
Case Report: Immunotherapy-containing fertility-sparing treatment integrated with preimplantation genetic testing resulting in live birth in Lynch syndrome-associated endometrial cancer. [PDF]
Zhao Y +5 more
europepmc +1 more source
ABSTRACT Congenital hypogonadotropic hypogonadism (CHH) is a rare group of disorders of gonadotropin deficiency, either isolated or as a part of multiple pituitary hormone deficiencies (MPHD). We aimed to describe the spectrum of presentation, diagnosis, and management practices of CHH spanning 30 years at an Australian tertiary paediatric centre. This
Minha Kook +3 more
wiley +1 more source
Exogenous Hormones and Their Clinical Implications for the Development and Growth of Meningioma Tumours. [PDF]
Roy H, Stavrakas M, Muquit S.
europepmc +1 more source
Digital Patient Decision Aids for Endometriosis Management: A Scoping Review
ABSTRACT Background Endometriosis treatment requires women to navigate complex, preference‐sensitive decisions. Patient Decision Aids (PtDAs) help patients make value‐aligned choices. However, the scope and quality of digital PtDAs for endometriosis, and the cap acity of conversational AI platforms to act as PtDAs, remain unclear.
Océane Pittet +5 more
wiley +1 more source
Response to progestin-based therapy in endometrial intraepithelial neoplasia: An exploratory biomarker study. [PDF]
Seay K +7 more
europepmc +1 more source
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Lillian Rose, Alexander S. Kauffman
wiley +1 more source
ABSTRACT Mounting evidence shows sex‐based differences in sleep experiences and outcomes, including the prevalence of insomnia disorder. However, the impact of biological sex on brain oscillations during sleep remains poorly understood, especially in the context of insomnia disorder. This is a notable gap, given that neurophysiological aspects of sleep
Nyissa A. Walsh +5 more
wiley +1 more source

