Abstract Background Hormone pre‐treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. Objectives To evaluate whether hormone pre‐treatment with gonadotropin‐releasing hormone (GnRH) agonists or progestogens could improve fertility in women with ...
Gaetano Riemma+8 more
wiley +1 more source
Effect of the menstrual cycle on performance of intermittent, high-intensity shuttle running in a hot environment [PDF]
The present study examined the impact of the menstrual cycle and oral contraceptive use on performance of high intensity intermittent running in the heat [31.0 (0.2) oC; 23.1 (0.9) % RH].
Nevill, ME, Sunderland, C
core +1 more source
Combined oral contraception: is there a resource for increased use?
Combined oral contraceptives (COCs) are a highly effective method for preventing unintended pregnancy, but unfortunately, the resource of their contraceptive and therapeutic potential is not used enough, and global unintended pregnancies account for ...
I. V. Kuznetsova+2 more
doaj +1 more source
Abstract Omaveloxolone is approved in the United States and the European Union for the treatment of patients with Friedreich ataxia aged ≥16 years. It is mainly metabolized by cytochrome P450 (CYP) 3A4 in vitro. Two drug–drug interaction studies (NCT04008186 and NCT05909644) were performed to evaluate (1) the effect of drug‐metabolizing enzymes (DMEs ...
Hamim Zahir+4 more
wiley +1 more source
Background Limited information is available on the effects of progestins on breast cancer progression and metastasis. Cell migration and invasion are central for these processes, and require dynamic cytoskeletal and cell membrane rearrangements for cell ...
Sitruk-Ware Regine+9 more
doaj +1 more source
The Relationship of Estrogen Changes With Sinonasal Symptoms and Disease in Women: A Scoping Review
The purpose of this scoping review was to assess the existing epidemiologic literature looking at the relationship of estrogen on sinonasal symptoms in women. PubMed and Embase were searched and 57 articles were chosen for analysis. Overall, the literature is heterogeneous but limited and so estrogen as mediator in sinonasal disease is an important ...
Snehitha Talugula+6 more
wiley +1 more source
PTEN as a predictive marker of response to conservative treatment in endometrial hyperplasia and early endometrial cancer. A systematic review and meta-analysis [PDF]
OBJECTIVE: Several markers have been studied to predict the responsiveness of endometrial hyperplasia (EH) and early endometrial cancer (EEC) to progestin therapy. PTEN has played a major role in this field, although its predictive significance is still
De Placido G+6 more
core +1 more source
Oral contraceptive progestins and angiotensin-dependent control of the renal circulation in humans [PDF]
Oral contraceptive (OC) use is associated with increased intra-renal renin-angiotensin-aldosterone system (RAA System) activity and risk of nephropathy, though the contribution of progestins contained in the OC in the regulation of angiotensin-dependent ...
Ahmed, Sofia B.+3 more
core +1 more source
Risk of endometrial cancer following estrogen replacement with and without progestins.
BACKGROUND Unopposed estrogen replacement therapy (i.e., estrogen without progestins) increases the risk of endometrial cancer. In this study, we examined the endometrial cancer risk associated with combined estrogen-progestin regimens currently in use ...
E. Weiderpass+7 more
semanticscholar +1 more source
Differential Expression of CRH, UCN, CRHR1 and CRHR2 in Eutopic and Ectopic Endometrium of Women with Endometriosis. [PDF]
Endometriosis is considered as a benign aseptic inflammatory disease, characterised by the presence of ectopic endometrium-like tissue. Its symptoms (mostly pain and infertility) are reported as constant stressors.
Jeschke, Udo+6 more
core +5 more sources