Results 71 to 80 of about 11,052 (225)

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas   +3 more
wiley   +1 more source

Second‐line MRI after expert transvaginal ultrasound in selected patients with suspected complex deep endometriosis: A prospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Second‐line MRI improves detection beyond expert transvaginal ultrasound in patients with suspected complex deep endometriosis, particularly for bowel and uterosacral ligament lesions, but at the cost of reduced specificity. These findings are consistent with a selective rather than routine role for MRI after expert transvaginal ultrasound.
Mira Rehal   +3 more
wiley   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

open access: yesBritish Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert   +2 more
wiley   +1 more source

Modern progestogens in the treatment of genital endometriosis

open access: yesРепродуктивная эндокринология
Objective of the review: to evaluate modern approaches to the use of progestogens for the treatment of endometriosis, using literature sources, to provide examples of their effectiveness in global and own practices. Analysis of literary data.
L.B. Markin, O.O. Matvienko
doaj   +1 more source

International Delphi consensus on feminising genital surgery in assigned‐male‐at‐birth individuals

open access: yesBJU International, EarlyView.
Objective To achieve an international expert consensus among surgeons on the indications, contraindications, and perioperative management of feminising genital surgery (FGS) for assigned‐male‐at‐birth (AMAB) individuals, using a Delphi process. Methods A two‐round on‐line Delphi survey (May–July 2025) followed by a final consensus meeting (September ...
Marta Pezzoli   +30 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

M1 macrophage‐derived exosomes aggravate diabetic nephropathy by regulating the WTAP/S1PR2 axis

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Background Diabetic nephropathy (DN) is a severe microvascular complication of diabetes mellitus. The specific role of M1 macrophage‐derived exosomes in DN progression remains largely unexplored. Methods THP‐1 monocytes were differentiated into M0 macrophages and polarized into M1 macrophages for exosome extraction.
Lei Li   +5 more
wiley   +1 more source

Pejerrey (Odontesthes bonariensis) Under Siege: Main Infectious Diseases and Their Role in Aquaculture and Wild Populations Amidst Environmental Change

open access: yesJournal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez   +4 more
wiley   +1 more source

The action of ovarian hormones in cardiovascular disease

open access: yesBiological Research, 2003
The incidence of cardiovascular disease (CAD) differs between men and women, in part because of differences in risk factors and hormones. This sexual dimorphism means a lower incidence in atherosclerotic diseases in premenopausal women, which ...
RODOLFO A MEDINA   +4 more
doaj  

Understanding exosomes in diabetic wound healing

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad   +4 more
wiley   +1 more source

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