Results 191 to 200 of about 3,538,014 (404)

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

A British Medical Association Lecture ON PROGNOSIS IN CARDIO-VASCULAR DISEASE [PDF]

, 1924
T. F. Cotton
openalex   +1 more source

A dynamic COVID-19 immune signature includes associations with poor prognosis

Nature Network Boston, 2020
Adam G. Laing, A. Lorenc, Irene del Molino del Barrio, Abhishek Das, M. Fish, L. Monin, M. Muñoz-Ruiz, Duncan R. McKenzie, T. Hayday, Isaac Francos-Quijorna, S. Kamdar, Magdalene Joseph, Daniel Davies, Richard Davis, Aislinn Jennings, I. Zlatareva, P. Vantourout, Yin Wu, Vasiliki Sofra, Florencia Cano, M. Greco, E. Theodoridis, Joshua Freedman, S. Gee, J. Chan, Sarah Ryan, Eva Bugallo-Blanco, P. Peterson, K. Kisand, L. Haljasmägi, L. Chadli, P. Moingeon, L. Martinez, B. Merrick, K. Bisnauthsing, Kate Brooks, Mohammad A. A. Ibrahim, J. Mason, Federico Lopez Gomez, K. Babalola, Sultan Abdul-Jawad, J. Cason, C. Mant, J. Seow, C. Graham, K. Doores, F. Di Rosa, J. Edgeworth, M. Shankar-Hari, A. Hayday   +49 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The Impact of Power Training on Muscle Power, Physical Performance, and Physical Functioning in Older Adults: A Descriptive Case Series

Clinical Interventions in Aging
Mohamed El Hadouchi,1– 4 Henri Kiers,1,2 Cindy Veenhof,2,5 Jaap Van Dieën3 1Institute for Human Movement Studies, University of Applied Sciences Utrecht, Utrecht, the Netherlands; 2Research Group Innovation of Human Movement Care, University of Applied ...
El Hadouchi M, Kiers H, Veenhof C, Van Dieën J   +3 more
doaj  

PATENT DUCTUS ARTERIOSUS SOME NOTES ON PROGNOSIS AND ON PULMONARY HYPERTENSION [PDF]

, 1955
Mark Campbell
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Cytological prognosis in cancer of the uterine cervix treated radiologically [PDF]

, 1955
Ruth M. Graham, John B. Graham
openalex   +1 more source

Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations

Diabetes & Metabolic syndrome: clinical Research & Reviews, 2020
A. Singh, Ritesh Gupta, Amerta Ghosh, Anoop Misra   +3 more
semanticscholar   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source