Results 61 to 70 of about 2,728,807 (361)

Prognosis in Tetraplegia [PDF]

BMJ, 1968
A total of 141 cases of traumatic tetraplegia were admitted to the Liverpool Paraplegic Centre between 1947 and 1967. Most of the deaths occurred within three months of injury, and comparison with other centres suggests that the early mortality could be reduced by more use of mechanical respirators.Urological complaints and pressure sores are hazards ...
J R, Silver, N O, Gibbon
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

[Prognosis of colorectal cancer and socio-economic inequalities].

, 2006
It is well established that socio-economic status is a major prognostic factor for many cancers, including colorectal cancer. The aims of this review are (i) to report epidemiological data showing how socio-economic status influences colorectal cancer ...
Mitry, Emmanuel, Rachet, Bernard
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Evidence of Aalenian-stage palaeofires in an extremely thick coal seam of the eastern Junggar Basin, Xinjiang, China

Frontiers in Earth Science
Scholars increasingly support the hypothesis that inertinite in coal is the product of incomplete combustion of plants in coal-forming peat swamps during fire events.
Qin Zhang, Shuo Feng, Bo Yang, Xin Li, Wenfeng Wang, Wenfeng Wang, Jijun Tian, Jijun Tian, Xingli Wang   +8 more
doaj   +1 more source

The science of clinical practice: disease diagnosis or patient prognosis? Evidence about "what is likely to happen" should shape clinical practice. [PDF]

, 2015
BACKGROUND: Diagnosis is the traditional basis for decision-making in clinical practice. Evidence is often lacking about future benefits and harms of these decisions for patients diagnosed with and without disease.
A Chauffard, A Vickers, AD Hingorani, Adam Timmis, AJ Vickers, Alastair D Hay, C Mar Del, CK Lee, DA Asch, Danielle A Van Der Windt, DE Newby, Douglas G Altman, E Rosenberg Charles, E Stolper, EAM Gale, EW Steyerberg, G-J Dinant, George Peat, H Downing, H Hemingway, Harry Hemingway, HG Welch, HM Krumholz, I Roberts, Ian Roberts, Independent UK Panel on Breast Cancer Screening, J Vestbo, J Wellwood, JC Hill, JG Jarvik, Jonathan J Deeks, Jutel Annemarie Goldstein, Kate M Dunn, L Ferrante di Ruffano, Linda LeResche, M Korff Von, M Roland, Michael Sharpe, Michael Von Korff, O Bruder, P Brown, Pablo Perel, PD White, Peter Croft, PM Bossuyt, R Aronowitz, R Moynihan, R Smith-Bindman, RA Aronowitz, Richard D Riley, Richard J Stevens, RK Simmons, RO Bonow, SJ Lord, SS Watson, Steffen E Petersen, TB Murdoch, WJ Katon   +57 more
core   +4 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Paleovegetation Community and Paleoclimate Succession in Middle Jurassic Coal Seams in Eastern Coalfields in Dzungaria Basin, China

Plants
The Dzungaria Basin is located north of Xinjiang and is one of the largest inland basins in China. The eastern coalfields in the Dzungaria Basin contain a large amount of coal resources, and the thickness of the coal seams is significant.
Xingli Wang, Shuo Feng, Wenfeng Wang, Qin Zhang, Jijun Tian, Changcheng Han, Meng Wang   +6 more
doaj   +1 more source

Characteristics and Prognosis of Autoimmune Encephalitis in the East of China: A Multi-Center Study [PDF]

, 2021
Shan Qiao, Huai-kuan Wu, Lingling Liu, Ranran Zhang, Meiling Wang, Tao Han, Shanchao Zhang, Xuewu Liu   +7 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source