Results 121 to 130 of about 295,913 (316)

Identification of CISD1 as a Prognostic Biomarker for Breast Cancer

, 2022
Xiao Liu,1 Qianqian Cui1,2 1Department of Breast Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang, 110042, People’s Republic of China; 2Department of Breast Surgery, Altaira Nursing Service ...
Liu X, Cui Q
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Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

TM7SF2 as a Potential Biomarker in Colorectal Cancer: Implications for Metastasis

Current Oncology
Colorectal cancer (CRC) is a commonly fatal cancer and ranks as the fourth most prevalent in men and third in women worldwide. While early-stage survival rates are high, they significantly decrease with recurrence and metastasis.
Inpyo Hong, Sooyoun Kim, Minho Lee, Seoin Han, Hak Chun Kim, Chong Woo Chu, Seong Geun Kim, Min Kyung Kim, Chang Jin Kim, Dong Hyun Kang, Tae Sung Ahn, Moo Jun Baek, Mudasir Hussain, Hyog Young Kwon, Dongjun Jeong   +14 more
doaj   +1 more source

Identifying Potential Effective Diagnostic and Prognostic Biomarkers in Sepsis by Bioinformatics Analysis and Validation

International Journal of General Medicine, 2022
Xu Huang, Jixiang Tan, Xiaoying Chen, Lin Zhao Department of Intensive Care Unit, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ChinaCorrespondence: Lin Zhao, Department of Intensive Care Unit, The First ...
Huang X, Tan J, Chen X, Zhao L
doaj  

Association between pretreatment haemoglobin levels and morphometric characteristics of the tumour, response to neoadjuvant treatment and long-term outcomes in patients with locally advanced rectal cancers

, 2013
Aim The study was carried out to investigate whether pretreatment haemoglobin (Hb) levels act as a biomar- ker in the management of patients with locally advanced rectal cancer.
Shabaan, A, Khan, AA, R. Glynne-Jones, Klonizakis, M, Glynne-Jones, R, A. A. Khan, M. Klonizakis, A. Shabaan   +7 more
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Bioinformatics Analysis of KIF1A Expression and Gene Regulation Network in Ovarian Carcinoma

International Journal of General Medicine, 2021
Xiaoyuan Lu,1,* Guilin Li,2,* Sicong Liu,3 Haihong Wang,1 Zhengzheng Zhang,1 Buze Chen1,4 1Department of Gynecology, The affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, Jiangsu, People’s Republic of China; 2Department of ...
Lu X, Li G, Liu S, Wang H, Zhang Z, Chen B   +5 more
doaj  

Assessment of prognostic biomarker studies for risk of bias using the ‘Quality Assessment in Prognostic studies’ (QUIPS) tool.

, 2016
Assessment of prognostic biomarker studies for risk of bias using the ‘Quality Assessment in Prognostic studies’ (QUIPS) tool.
Martin Brand (623595), Yandiswa Yolanda Yako (292914), Martin Smith (51258), Deirdré Kruger (3171861)   +3 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Pretreatment neutrophil–lymphocyte ratio: useful prognostic biomarker in hepatocellular carcinoma

, 2018
Marc Najjar,1 Surbhi Agrawal,1 Jean C Emond,1 Karim J Halazun1,2 1Department of Surgery, Center for Liver Disease and Transplantation, Columbia University Medical Center, New York Presbyterian Hospital, New York, NY, USA; 2Department of Surgery, Division
Agrawal S, Emond JC, Halazun KJ, Najjar M   +3 more
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