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Prognostic and Predictive Biomarkers in Cancer
Current Cancer Drug Targets, 2014With the recent emergence of novel technologies, the field of biomarker discovery has been the subject of intense research and activity. Major advances in cancer control will be greatly aided by early detection for the diagnosis and treatment of cancer in its pre-invasive state.
Meera, Nair +2 more
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A prognostic biomarker of corneal repair
Nature Biomedical Engineering, 2019A non-invasive biomarker of the degree of collective order of monolayers of corneal endothelial cells cultured for transplantation predicts the long-term prognosis of corneal restoration in patients.
Jodhbir S, Mehta +2 more
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MARCO is a potential prognostic and immunotherapy biomarker
International Immunopharmacology, 2022Macrophage receptor with collagenous structure (MARCO), a novel immune checkpoint expressed on tumor-associated macrophages, has antitumor therapeutic properties. However, the association between MARCO and patient prognosis, immune infiltration, and ICI immunotherapy needs to be studied urgently.MARCO distribution in cancer tissues was investigated ...
Qingyu Dong +6 more
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Prognostic Biomarkers for Hodgkin Lymphoma
Pediatric Hematology and Oncology, 2015The prognosis of patients with classical Hodgkin lymphoma following chemo- and radiotherapy has been excellent during the last 4 decades. However, the development of secondary malignancies is of major concern. Therefore, the reduction of radiotherapy application is a major objective of ongoing clinical trials.
Martin S, Staege +4 more
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Prognostic biomarkers in malignant lymphomas
Leukemia & Lymphoma, 2010There has recently been a rapid expansion in research aimed at identifying biomarkers that could improve the prognosis for patients with various subtypes of malignant lymphoma. Genomic and genetic studies have led to the identification of biological and clinical subgroups of diffuse large B-cell lymphomas with distinct underlying molecular features ...
Gascoyne, Randy D. +3 more
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Prognostic and predictive biomarkers in melanoma
PathologyBiomarkers help to inform the clinical management of patients with melanoma. For patients with clinically localised primary melanoma, biomarkers can help to predict post-surgical outcome (including via the use of risk prediction tools), better select patients for sentinel lymph node biopsy, and tailor catch-all follow-up protocols to the individual ...
Nigel G. Maher +3 more
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Prognostic biomarkers in thyroid cancer
Virchows Archiv, 2014Thyroid carcinomas represent a challenging problem from the prognostic standpoint. Despite an overall good prognosis of the most frequent endocrine malignancy, 10-15 % of papillary thyroid carcinomas (PTCs) turn refractory to radioactive iodine therapy. The increased incidence of thyroid cancer has led to the search for solid prognostic biomarkers that
Paula, Soares +4 more
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Novel Prognostic Biomarkers in Colorectal Cancer
Digestive Diseases, 2012The main predictor of outcome of patients with colorectal cancer (CRC) remains the TNM staging system. Biomarkers, i.e. biological indicators of disease progression or of responsiveness to a pharmacological intervention, are expected to be of help in the management of CRC.
A. Malesci, L. Laghi
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Prognostic biomarkers for cholangiocarcinoma and their clinical implications
Expert Review of Anticancer Therapy, 2018Cholangiocarcinoma (CCA) is a poorly prognostic cancer with limited treatment options. Most patients have unresectable tumors when they are diagnosed and the chemotherapies provided are of limited benefit. Prognostic markers are therefore necessary to predict the disease outcome, risk of relapse, or to suggest the best treatment option.
Charupong, Saengboonmee +3 more
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SLC12A9 Is an Immunological and Prognostic Biomarker for Glioma
GeneGlioma is one of the most common malignant brain tumors. It has a high rate of progression and a poor prognosis, and effective biomarkers still need to be identified. The solute carrier family 12 (SLC12) family has been reported to be involved in various physiological and pathological processes, but their functional roles in glioma remain unclear.Using
Danting Li, Peilin Zheng, Shoujun Huang
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