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SLC12A9 Is an Immunological and Prognostic Biomarker for Glioma
GeneGlioma is one of the most common malignant brain tumors. It has a high rate of progression and a poor prognosis, and effective biomarkers still need to be identified. The solute carrier family 12 (SLC12) family has been reported to be involved in various physiological and pathological processes, but their functional roles in glioma remain unclear.Using
Danting Li, Peilin Zheng, Shoujun Huang
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Biomarker: Predictive or Prognostic?
Journal of Clinical Oncology, 2015To demonstrate that a biomarker is predictive of treatment benefit, the study requires biomarker status on all patients as well as patients who were treated with the agent of interest and patients not so treated, preferably in the context of a randomized study.
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Prognostic factors and biomarkers of penile carcinoma
Expert Opinion on Medical Diagnostics, 2008Penile squamous cell carcinoma (SCC) is a rare malignancy with highest incidence in underdeveloped and developing countries. Oncogenic human papilloma virus (HPV) DNA, mainly types 16 and 18, are found in ∼ 100% of patients with uterine cervix carcinoma. The incidence of this virus in SCC and its variations range from 30.5 to 80%. Despite controversies,
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Predictive and prognostic biomarkers in urological tumours
PathologyAdvancements in cutting-edge molecular profiling techniques, such as next-generation sequencing and bioinformatic analytic tools, have allowed researchers to examine tumour biology in detail and stratify patients based on factors linked with clinical outcome and response to therapy. This manuscript highlights the most relevant prognostic and predictive
Alessia, Cimadamore +11 more
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Predictive and prognostic molecular biomarkers in lymphomas
PathologyRecent advances in molecular diagnostics have markedly expanded our understanding of the genetic underpinnings of lymphomas and catalysed a transformation in not just how we classify lymphomas, but also how we treat, target, and monitor affected patients.
J. Bryan Iorgulescu +2 more
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Lamin B1 is a potential therapeutic target and prognostic biomarker for hepatocellular carcinoma
Bioengineered, 2022Heping Kan
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