Results 101 to 110 of about 866,858 (352)
Evaluating methodological quality of Prognostic models Including Patient-reported HeAlth outcomes in oncologY (EPIPHANY): A systematic review protocol [PDF]
, 2018 Introduction While there is mounting evidence of the independent prognostic value of patient-reported outcomes (PROs) for overall survival (OS) in patients with cancer, it is known that the conduct of these studies may hold a number of methodological ...
Anota, Amélie +4 more
core +2 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Frontiers in ImmunologyBackgroundRadiotherapy elicits immune activation, thereby synergistically enhancing systemic tumor control when combined with immunotherapy. Glutaminase (GLS), a key enzyme for glutamine metabolism, has been found to regulate glutamine availability ...
Peicheng Jiang +6 more
doaj +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
BiomedicinesBackground: Colorectal cancer (CRC) ranks as the third most common cancer worldwide. Tertiary lymphoid structures (TLSs), organized immune cell aggregates in non-lymphoid tissues, are linked to chronic inflammation and tumorigenesis. However, the precise
Leyi Zhao +6 more
doaj +1 more source
External validation of a prognostic model for 1-year survival after fragility hip fracture: A retrospective cohort study [PDF]
, 2022 Hairui Fu +7 more
openalex +1 more source
Economic Growth in Georgia: Historical Perspectives and Prognosis [PDF]
While output declined in virtually all transition economies in the initial years, the speed and extent of the recovery that followed has varied widely across these countries. The paper examines some aspects of transition experiences of 1990s and dynamics
Alexander Milnikov +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Frontiers in ImmunologyBackgroundProgrammed Cell death (PCD) encompasses a spectrum of genetically regulated cell death processes and plays a double-edged sword role in neoplastic progression and therapeutic resistance of Triple-Negative Breast Cancer(TNBC)through the tumor ...
Xiaowen Ma +4 more
doaj +1 more source
Prognostic indication of power cable degradation
, 2013 The reliability and the health performance of network assets are of a great interest due to power network operators. This project investigates methods of developing a prognostic capability for evaluating the health and long term performance of ageing ...
Christou, S. +3 more
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