Results 61 to 70 of about 5,086,656 (300)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Prevalence of malnutrition and its prognostic impact in lung metastasis patients treated with SBRT: insights from NRI, CONUT, NRS, and PNI

Frontiers in Nutrition
ObjectiveMalnutrition is a significant and modifiable prognostic factor in patients with pulmonary metastases undergoing stereotactic body radiotherapy (SBRT).
Yunjie Zhang, Jingjing Shan, Benxing Gu, Runying Huang, Hai Liu   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Is the Prognostic Nutritional Index a Predictor of Urolithiasis?

Journal of Urological Surgery
Objective: Prognostic nutritional index (PNI) is a parameter that reflects nutritional status and inflammation. It is calculated from serum albumin and lymphocyte count. Our study investigated whether PNI has a predictive value in urolithiasis. Materials and Methods: Data of patients who applied to A & gbreve;r & imath; Training and Research Hospital ...
Dereköylü, Engin, Çoşkun, Çağrı, Aydın, Uğur, Tarım, Kayhan   +3 more
openaire   +2 more sources

Association Between the Malnutrition Status and All‐Cause Mortality in Patients With Moderate and Severe Aortic Stenosis: A Prospective Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Malnutrition status is an important predictor of prognosis in patients after aortic valve replacement. However, the prognostic value of malnutrition status in patients with moderate‐to‐severe aortic stenosis is unclear.
Bingzhen Li, Shaozhao Zhang, Chaoguang Xu, Mengting Huang, Zhenyu Xiong, Ziwen Hui, Xinxue Liao, Jilin Li, Jianying Chen, Xiaodong Zhuang   +9 more
doaj   +1 more source

Nutritional and prognostic correlates of bioimpedance indexes in hemodialysis patients

Kidney International, 1996
We carried out a cross sectional and longitudinal study to assess whether bioimpedance indexes (resistance, Rz; reactance, Xc; phase angle, PA) reflect the nutritional status of hemodialysis (HD) patients, and bear a significant association with their long-term survival.
Maggiore, Quirino, Nigrelli, Santi, Ciccarelli, Carla, Grimaldi, Cristina, Rossi, Giuseppe A., Michelassi, Claudio   +5 more
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Diagnostic utility and discriminative ability of cholesterol-modified prognostic nutritional index and inflammatory indicators in colorectal cancer: a retrospective case-control study

Scientific Reports
Malnutrition and altered biochemical parameters are common in colorectal cancer (CRC) patients. This study aimed to evaluate the diagnostic utility and discriminative ability of nutritional indices, including cholesterol-modified prognostic nutritional ...
Berrin Papila, Sinem Durmus, Murad Guliyev, Ozkan Alan, Nebi Serkan Demirci, Remise Gelisgen, Cigdem Papila, Hafize Uzun   +7 more
doaj   +1 more source

Change in Nutritional Status and Dysphagia after Resection of Head and Neck Cancer

, 2021
Nutritional status is well-known to influence patient recovery after resection of head and neck cancer (HNC). The influence of preoperative nutritional status on dysphagia was assessed in patients who underwent surgical resection of HNC along with the ...
Ayumi Sadakane-Sakuramoto, Nobuhide Horii, Tomoki Nanto, Kazuma Sugahara, Yuta Nakao, Yoko Hasegawa, Syota Saito, Kazuhisa Domen, Takahiro Ono, Hiromitsu Kishimoto   +9 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source