Results 71 to 80 of about 5,086,656 (300)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Prognostic prediction by hypermetabolism varies depending on the nutritional status in early amyotrophic lateral sclerosis

Scientific Reports, 2021
To examine whether hypermetabolism could predict the prognosis of early amyotrophic lateral sclerosis (ALS) patients with differing nutritional profiles.
Ryutaro Nakamura, Mika Kurihara, Nobuhiro Ogawa, Akihiro Kitamura, Isamu Yamakawa, Shigeki Bamba, Mitsuru Sanada, Masaya Sasaki, Makoto Urushitani   +8 more
doaj   +1 more source

Prognostic significance of preoperative prognostic nutritional index in hepatocellular carcinoma: a meta-analysis [PDF]

HPB, 2018
To date, epidemiological evidence of the association between preoperative prognostic nutritional index (PNI) and the prognosis of hepatocellular carcinoma (HCC) remains controversial.A literature search was performed in the databases of PubMed, Embase, and Web of Science.
Zhongran, Man, Qing, Pang, Lei, Zhou, Yong, Wang, Xiaosi, Hu, Song, Yang, Hao, Jin, Huichun, Liu   +7 more
openaire   +2 more sources

Prognostic Nutritional Index in Patients with Both Vertebral and Non-Vertebral Osteoporotic Fractures [PDF]

Objective: The prognostic nutritional index (PNI) is an index used to evaluate the basic nutritional status of patients with osteoporosis. However, it is not yet clear whether PNI can be used as an indicator of osteoporotic fracture.
Fulya Bakılan, Gizem Sarıçimen, BAKILAN, FULYA, Saricimen, Gizem   +3 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Prognostic Nutritional Index Predicts Outcomes of Gastrectomy in the Elderly

World Journal of Surgery, 2012
AbstractBackgroundOwing to the increased life expectancy, elderly patients with gastric cancer is also increasing. Onodera’s prognostic nutritional index (PNI) is an assessment tool for nutritional status of surgical patients and possibly predicts prognosis of the patients.
Masayuki, Watanabe, Masaaki, Iwatsuki, Shiro, Iwagami, Takatsugu, Ishimoto, Yoshifumi, Baba, Hideo, Baba   +5 more
openaire   +3 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Clinical significance of prognostic nutritional index in patients with glioblastomas

Medicine, 2018
Abstract Preoperative prognostic nutritional index (PNI) has been proven to be associated with clinical outcomes in patients with malignancies. However, data regarding the role of PNI in human glioblastomas (GBMs) is lacking. We, therefore, aimed to investigate the association between PNI and clinical parameters and survival in
Ding, Jin-Duo, Yao, Kun, Wang, Peng-Fei, Yan, Chang-Xiang   +3 more
openaire   +2 more sources

The relationship between prognostic nutritional index and treatment response in patients with metastatic renal cell cancer

, 2019
Introduction and aim To investigate the effect of the prognostic nutritional index on treatment response and survival in patients with metastatic renal cell cancer.
Yucel, Kadriye Bir, Kucukarda, Ahmet, Demirci, Umut, Bilgin, Burak, Yildiz, Birol, Hizal, Mutlu, Utkan, Gungor, Ucar, Gokhan, Arslan, Cagatay, Sendur, Mehmet Ali, ÇİÇİN, İRFAN, ÜRÜN, YÜKSEL, Erturk, Ismail, Yildirim, Nuriye, KILIÇKAP, SAADETTİN, Karakaya, Serdar, Karadurmus, Nuri, Yucel, KADRİYE, Bir Yücel, Kadriye, Yasar, Hatime Arzu, Taban, Hakan   +20 more
core   +2 more sources

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source