Results 31 to 40 of about 823,140 (217)

Prognosis Research Strategy (PROGRESS) 3: prognostic model research.

PLoS Medicine, 2013
Prognostic models are abundant in the medical literature yet their use in practice seems limited. In this article, the third in the PROGRESS series, the authors review how such models are developed and validated, and then address how prognostic models ...
Ewout W Steyerberg, Karel G M Moons, Danielle A van der Windt, Jill A Hayden, Pablo Perel, Sara Schroter, Richard D Riley, Harry Hemingway, Douglas G Altman, PROGRESS Group   +9 more
doaj   +1 more source

Multivariable prediction models for health care spending using machine learning: a protocol of a systematic review

Diagnostic and Prognostic Research, 2022
Background With rising cost pressures on health care systems, machine-learning (ML)-based algorithms are increasingly used to predict health care costs.
Andrew W. Huang, Martin Haslberger, Neto Coulibaly, Omar Galárraga, Arman Oganisian, Lazaros Belbasis, Orestis A. Panagiotou   +6 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Cortical activations induced by electrical versus vibrotactile finger stimulation using EEG

NeuroImage
Somatosensory evoked potentials (SEPs) recorded with electroencephalography offer insights into cortical responses to tactile stimulation, typically elicited through temporally precise electrical stimulation.
Anaëlle Alouit, Martine Gavaret, Céline Ramdani, Påvel G. Lindberg, Lucile Dupin   +4 more
doaj   +1 more source

Broad external validation of a multivariable risk prediction model for gastrointestinal malignancy in iron deficiency anaemia

Diagnostic and Prognostic Research, 2021
Background Using two large datasets from Dorset, we previously reported an internally validated multivariable risk model for predicting the risk of GI malignancy in IDA—the IDIOM score.
Orouba Almilaji, Gwilym Webb, Alec Maynard, Thomas P. Chapman, Brian S. F. Shine, Antony J. Ellis, John Hebden, Sharon Docherty, Elizabeth J. Williams, Jonathon Snook   +9 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Development of risk prediction models to predict urine culture growth for adults with suspected urinary tract infection in the emergency department: protocol for an electronic health record study from a single UK university hospital

Diagnostic and Prognostic Research, 2020
Background Urinary tract infection (UTI) is a leading cause of hospital admissions and is diagnosed based on urinary symptoms and microbiological cultures.
Patrick Rockenschaub, Martin J. Gill, David McNulty, Orlagh Carroll, Nick Freemantle, Laura Shallcross   +5 more
doaj   +1 more source

Knowledge translation of prediction rules: methods to help health professionals understand their trade-offs

Diagnostic and Prognostic Research, 2021
Clinical prediction models are developed with the ultimate aim of improving patient outcomes, and are often turned into prediction rules (e.g. classifying people as low/high risk using cut-points of predicted risk) at some point during the development ...
K. Hemming, M. Taljaard
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Investigating Age-Dependent Oxygenation and Blood Perfusion in a Mouse Model of Peripheral Artery Disease (PAD) Using Multispectral Optoacoustic Tomography (MSOT), Laser Speckle Contrast Imaging (LSCI) and Histology

Diagnostics
Background/Objectives: Peripheral artery disease (PAD) is frequently asymptomatic, requiring non-invasive approaches for disease evaluation and therapy monitoring.
Bushra Afzal, Vy Tran, Na Nguyen, Savannah Qui-Tam Le, Tam Nguyen, Kytai T. Nguyen, Li Liu, Ralph P. Mason   +7 more
doaj   +1 more source