Results 41 to 50 of about 823,140 (217)

Purines for Rapid Identification of Stroke Mimics (PRISM): study protocol for a diagnostic accuracy study

Diagnostic and Prognostic Research, 2021
Background Rapid treatment of stroke improves outcomes, but accurate early recognition can be challenging. Between 20 and 40% of patients suspected to have stroke by ambulance and emergency department staff later receive a non-stroke ‘mimic’ diagnosis ...
Lisa Shaw, Sara Graziadio, Clare Lendrem, Nicholas Dale, Gary A. Ford, Christine Roffe, Craig J. Smith, Philip M. White, Christopher I. Price   +8 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Symbiopersonal intelligence towards symbiotic and personalized digital medicine

Fundamental Research
In this perspective, we introduce the concept of Symbiopersonal Intelligence (SymAI)—a specialized form of artificial intelligence designed to facilitate and optimize symbiotic interactions between individuals and intelligent devices in digital medicine.
Alfred Mensah, Qiwen Bao, Zhaonan Zhang, Ya Chen, Qing Jiang, Pingqiang Cai   +5 more
doaj   +1 more source

The index of prediction accuracy: an intuitive measure useful for evaluating risk prediction models

Diagnostic and Prognostic Research, 2018
Background Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional investigation of calibration.
Michael W. Kattan, Thomas A. Gerds
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Comparison of methods for predicting COVID-19-related death in the general population using the OpenSAFELY platform

Diagnostic and Prognostic Research, 2022
Background Obtaining accurate estimates of the risk of COVID-19-related death in the general population is challenging in the context of changing levels of circulating infection.
The OpenSAFELY Collaborative, Elizabeth J. Williamson, John Tazare, Krishnan Bhaskaran, Helen I. McDonald, Alex J. Walker, Laurie Tomlinson, Kevin Wing, Sebastian Bacon, Chris Bates, Helen J. Curtis, Harriet J. Forbes, Caroline Minassian, Caroline E. Morton, Emily Nightingale, Amir Mehrkar, David Evans, Brian D. Nicholson, David A. Leon, Peter Inglesby, Brian MacKenna, Nicholas G. Davies, Nicholas J. DeVito, Henry Drysdale, Jonathan Cockburn, William J. Hulme, Jessica Morley, Ian Douglas, Christopher T. Rentsch, Rohini Mathur, Angel Wong, Anna Schultze, Richard Croker, John Parry, Frank Hester, Sam Harper, Richard Grieve, David A. Harrison, Ewout W. Steyerberg, Rosalind M. Eggo, Karla Diaz-Ordaz, Ruth Keogh, Stephen J. W. Evans, Liam Smeeth, Ben Goldacre   +44 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Rebecca J. Deyell, Lesleigh Abbott, Tony H. Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +21 more
wiley   +1 more source

A comparison of landmark methods and time-dependent ROC methods to evaluate the time-varying performance of prognostic markers for survival outcomes

Diagnostic and Prognostic Research, 2019
Background Prognostic markers use an individual’s characteristics at a given time to predict future disease events, with the ultimate goal of guiding medical decision-making.
Aasthaa Bansal, Patrick J. Heagerty
doaj   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source