Results 61 to 70 of about 9,324 (243)
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
Metrics for Offline Evaluation of Prognostic Performance [PDF]
International Journal of Prognostics and Health Management, 2010 Prognostic performance evaluation has gained significant attention in the past few years.Currently, prognostics concepts lack standard definitions and suffer from ambiguous and inconsistent interpretations.
Sankalita Saha +4 more
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm +10 more
wiley +1 more source
NCFU - ENTERING THE 6TH TECHNOLOGICAL CYCLE (SCIENTOMETRIC ANALYSIS)
Вестник Северо-Кавказского федерального университета, 2022 Of the thirteen problematic positions within the 6th TC, the research at the NCFU is held in 5 areas, which is done at thirteen departments and one research center.
Anna V. Savtsova, Victor M. Averbukh
doaj
Pediatric Blood &Cancer, EarlyView.ABSTRACT Although most malignant germ cell tumors (GCTs) are highly curable with cisplatin‐based therapy, options for patients with multiply relapsed/refractory disease remain limited. For this population, we report the first pediatric use of gemcitabine, docetaxel, melphalan, and carboplatin (GemDMC) as part of sequential cycles of high‐dose ...
Maria Frost +10 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender +17 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack +39 more
wiley +1 more source
Applied SciencesThe growing use of lithium-ion batteries (LIBs) in electric vehicles has accelerated the need for efficient strategies to extend their lifespan through second-life applications, where retired batteries are repurposed for stationary storage and other less
Abdel Rahman El Khatib +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt +76 more
wiley +1 more source
Aerospace, 2019 Traditional hydraulic servomechanisms for aircraft control surfaces are being gradually replaced by newer technologies, such as Electro-Mechanical Actuators (EMAs). Since field data about reliability of EMAs are not available due to their recent adoption,
Matteo D. L. Dalla Vedova +3 more
doaj +1 more source