Results 91 to 100 of about 4,968,629 (297)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Understanding Evaluations of Environmental Education Programs [PDF]

This article provides instruction on how to read and interpret an evaluation of an environmental education program. Topics include the benefits of conducting a sound evaluation and finding programs with similar goals as examples.

core  

Alcoa Foundation's Global Internship Program for Unemployed Youth Midterm Evaluation Snapshot [PDF]

, 2015
Alcoa Foundation's Global Internship Program for Unemployed Youth Midterm Evaluation ...

core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Does subsidized childcare help poor working women in urban areas? [PDF]

High urbanization rates in Latin America are accompanied by an increase in women's participation in the labor force and the number of households headed by single mothers.
Coj, Nora, de la Briere, Benedicte, Hallman, Kelly, Quisumbing, Agnes R., Ruel, Marie T.   +4 more
core   +3 more sources

Program evaluation of postgraduate obstetrics and gynecology training in Lao people’s democratic republic - using the CIPP model

BMC Medical Education
Background The obstetrics and gynaecology (OB-GYN) residency training program in Lao People’s Democratic Republic (PDR) began in 2003 based on the Millennium Development Goals (MDGs) and ‘Reproductive, maternal, newborn, and child health interventions ...
Panima Chanthalangsy, Byung-Il Yeh, Seong Jin Choi, Yon Chul Park   +3 more
doaj   +1 more source

Designing, Developing, and Sustaining Doctoral Programs in a Post-Pandemic Age

Impacting Education
This special themed issue of Impacting Education, Designing, Developing, and Sustaining Doctoral Programs in a Post-Pandemic Age, focuses on ways in which educators have used the pandemic as an opportunity in their doctoral programs for reimagination and
Rebecca Harper
doaj   +1 more source

The Contribution of Metaevaluation to Program Evaluation: Proposition of a Model

Journal of MultiDisciplinary Evaluation, 2009
Background: This theoretical article points to the fundamental difference between meta-analysis and metaevaluation. A model of metaevaluation for social programs is presented based on prior practical research.
Helga Hedler, Namara G. Ribeiro
doaj   +1 more source

Increasing Youth Safety and Responsible Behavior Online: Putting in Place Programs that Work. [PDF]

, 2011
Hundreds of programs are being developed to promote safe and responsible online behavior among youth. They are being successfully marketed and eagerly adopted because of their appealing content, exciting graphics, engaging games, catchy phrases and cool ...
Finkelhor, David, Jones, Lisa M.
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source