Results 111 to 120 of about 11,283,501 (304)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Findings brief : external review of the Ecosystem Approaches to Human Health Program [PDF]

, 2007
French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme Écosystèmes et santé humaineThis findings brief is based on the report "External Review of the IDRC Ecohealth Program Initiative," by Jacobo ...
IDRC. Evaluation Unit
core   +1 more source

Investigating dimensions of instructor trust using the words of undergraduate STEM students

Frontiers in Education
IntroductionRecent work has shown that student trust in their instructor is a key moderator of STEM student buy-in to evidence-based teaching practices (EBTs), enhancing positive student outcomes such as performance, engagement, and persistence. Although
Kathy Zhang, Julia C. Gill, Tong Zhang, Lia Crowley, Juliette Bennie, Henry Wagner, Melanie Bauer, David Hanauer, Xinnian Chen, Mark J. Graham   +9 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Findings brief : external review of the Rural Poverty and Environment Program

, 2009
French version available in IDRC Digital Library: Constatations en bref de l'examen externe du programme Pauvreté rurale et environnementThis findings brief is based on the report, "External Evaluation of the Rural Poverty and Environment (RPE) Program
IDRC. Evaluation Unit
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Evaluation of Dental Programs for Children

American Journal of Public Health and the Nations Health, 1938
This chart (Figure I) is to be used in surveying dental needs of school age children. It is hoped that the designation by the American Society for the Promotion of Dentistry for Children, the American Dental Association, and the proposed sanction of the American Public Health Association, will result in widespread adoption.
openaire   +3 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Pharmacy Programs & Evaluations

INNOVATIONS in pharmacy, 2018
Article 1: Positive Deviants for Medication Therapy Management: Behaviors and Delivery Strategies That Distinguish the Highest Performing Community Pharmacies Omolola A. Adeoye, PharmD; Leslie M. Lake, PharmD; Karen S. Hudmon, DrPH, MS; Alan J. Zillich, PharmD, FCCP; Margie E. Snyder, PharmD, MPH, FCCPArticle 2: Establishing Community Pharmacy Links to
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source