Results 31 to 40 of about 1,266,471 (355)

p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death [PDF]

, 2016
p53 is a central factor in tumor suppression as exemplified by its frequent loss in human cancer. p53 exerts its tumor suppressive effects in multiple ways, but the ability to invoke the eradication of damaged cells by programmed cell death is considered
Baudot, Alice D., Crighton, Diane, O'Prey, Jim, Ryan, Kevin M., Sierra Gonzalez, Pablo, Somers, Joanna   +5 more
core   +2 more sources

Induction of Apoptotic Cell Death Leads to the Development of Bacterial Rot Caused by Pseudomonas cichorii

Molecular Plant-Microbe Interactions, 2006
Pseudomonas cichorii is the major causal agent of bacterial rot of lettuce. Collapse and browning symptoms were observed in lettuce leaf tissue from 15 to 24 h after inoculation (HAI) with P.cichorii; superoxide anion generation was detected at 1 to 6 ...
Akinori Kiba, Yasutaka Sangawa, Kouhei Ohnishi, Nan Yao, Pyoyun Park, Hitoshi Nakayashiki, Yukio Tosa, Shigeyuki Mayama, Yasufumi Hikichi   +8 more
doaj   +1 more source

Nitric Oxide and Reactive Oxygen Species Do Not Elicit Hypersensitive Cell Death but Induce Apoptosis in the Adjacent Cells During the Defense Response of Oat

Molecular Plant-Microbe Interactions, 2004
Nitric oxide (NO) acts as a signaling molecule in many cellular responses in plants and animals. Oat plants (Avena sativa L.) evoke the hypersensitive response (HR), which shares morphological and biochemical features with mammalian apoptosis, such as ...
Yasuomi Tada, Tomoyo Mori, Takeshi Shinogi, Nan Yao, Satsuki Takahashi, Shigeyuki Betsuyaku, Masaru Sakamoto, Pyoyun Park, Hitoshi Nakayashiki, Yukio Tosa, Shigeyuki Mayama   +10 more
doaj   +1 more source

Alternative cell death pathways and cell metabolism [PDF]

, 2013
While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
core   +2 more sources

Regulation of a Virus-Induced Lethal Disease in Tomato Revealed by LongSAGE Analysis

Molecular Plant-Microbe Interactions, 2007
Infection of Cucumber mosaic virus (CMV) and D satellite RNA (satRNA) in tomato plants induces rapid plant death, which has caused catastrophic crop losses.
Saeed Irian, Ping Xu, Xinbin Dai, Patrick X. Zhao, Marilyn J. Roossinck   +4 more
doaj   +1 more source

Development of a Lesion-Mimic Phenotype in a Transgenic Wheat Line Overexpressing Genes for Pathogenesis-Related (PR) Proteins Is Dependent on Salicylic Acid Concentration

Molecular Plant-Microbe Interactions, 2003
In the course of coexpressing genes for pathogenesis-related (PR) proteins for a class IV chitinase and an acidic glucanase in transgenic wheat plants, we regenerated a wheat line that developed necrotic lesions containing dead cells in the T2 and ...
Ajith Anand, Eric A. Schmelz, Subbaratnam Muthukrishnan   +2 more
doaj   +1 more source

The convergence of radiation and immunogenic cell death signaling pathways. [PDF]

, 2012
Ionizing radiation (IR) triggers programmed cell death in tumor cells through a variety of highly regulated processes. Radiation-induced tumor cell death has been studied extensively in vitro and is widely attributed to multiple distinct mechanisms ...
Barcellos-Hoff, Mary H, Demaria, Sandra, Formenti, Silvia C, Golden, Encouse B, Pellicciotta, Ilenia   +4 more
core   +2 more sources

The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]

, 2011
The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali, Asher, Viren, Averil Warren, Heidi Sowter, Raheela Khan, Robert Shaw, Viren Asher   +6 more
core   +5 more sources

Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae [PDF]

, 2005
Prova tipográfica (In Press)During the last years, several reports described an apoptosis-like programmed cell death process in yeast in response to different environmental aggressions.
Baker, Balzan, Brown, Chan, Del Carratore, Dumont, Edwards, Fahrenkrog, Fannjiang, Galvez, Goldstein, Granot, Haugland, Heeren, Herker, Hoover, Huh, Laun, Liao, Ligr, Liu, Ludovico, Ludovico, Ludovico, Ludovico, Madeo, Madeo, Madeo, Madeo, Manon, Matthews, Mockridge, Morales, Pozniakovsky, Reilly, Severin, Silva, Vieira, Wadskog, Wissing, Wright, Wysocki, Yamaki   +42 more
core   +1 more source

Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to the Canonical Pathway for Apoptosis in Caenorhabditis elegans [PDF]

, 2012
Caspases are cysteine proteases that can drive apoptosis in metazoans and have critical functions in the elimination of cells during development, the maintenance of tissue homeostasis, and responses to cellular damage. Although a growing body of research
A Cauwels, A Degterev, A Gartner, A Raj, AH Wyllie, AM Chinnaiyan, B Conradt, B Pinan-Lucarre, B Schumacher, BT Hyman, D Xue, D Xue, Daniel P. Denning, DJ Dwyer, DJ Hoeppner, DP Denning, DT Harris, E Arama, E Pourkarimi, EC Andersen, EH Cheng, EM Hedgecock, ES Blum, F Chen, F Madeo, F Simmer, H. Robert Horvitz, HC Chang, Hermann Steller, HM Ellis, HT Schwartz, J Yuan, J Yuan, JE Sulston, JE Sulston, JF Kerr, JM Kinchen, JY Yuan, K Xu, M Darland-Ransom, MC Abraham, MC Abraham, MO Hengartner, MO Hengartner, NA Thornberry, PW Reddien, RA Lockshin, RE Ellis, S Brenner, S Harbinder, S Qi, S Seshagiri, S Shaham, S Shaham, S Shaham, SA Susin, T Hirose, TL Gumienny, V Venegas, VA Fadok, Victoria Hatch, X Geng, X Geng, X Wang, X Yang, Z Zhou   +65 more
core   +4 more sources