Results 41 to 50 of about 6,837,118 (237)

Regulation of cell death in cancer - possible implications for immunotherapy [PDF]

, 2013
Since most anticancer therapies including immunotherapy trigger programmed cell death in cancer cells, defective cell death programs can lead to treatment resistance and tumor immune escape.
Simone Fulda, Simone eFulda, Fulda, Simone   +2 more
core   +1 more source

Programmed cell death in aging [PDF]

Ageing Research Reviews, 2015
Programmed cell death (PCD) pathways, including apoptosis and regulated necrosis, are required for normal cell turnover and tissue homeostasis. Mis-regulation of PCD is increasingly implicated in aging and aging-related disease. During aging the cell turnover rate declines for several highly-mitotic tissues. Aging-associated disruptions in systemic and
openaire   +2 more sources

The meaning of death : evolution and ecology of apoptosis in protozoan parasites [PDF]

, 2011
This work was funded by the Wellcome Trust (SER: WT082234MA; http://www.wellcome.ac.uk/), the NERC (LCP: studentship), the Royal Society of London (AG: University Research Fellowship; http://royalsociety.org/), and Balliol College, University of Oxford ...
Colegrave, Nick, Sarah E Reece, Sarah E. Reece, Pollitt Laura C., Colegrave Nick, Reece, Sarah E., Gardner, A, Pollitt, Laura C., Colegrave, N, Laura C Pollitt, Nick Colegrave, Gardner Andy, Gardner, Andy, Pollitt, LC, Reece, SE, Reece Sarah E., Andy Gardner, Laura C. Pollitt   +17 more
core   +1 more source

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells [PDF]

, 2012
For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner.
Gabor Barna (146087), Pal I Bauer, Istvan Petak, Mihalik, Rudolf, Zsuzsanna A Dunai, Gergely Imre, Istvan Petak (5648680), Pal I. Bauer (144904), Gergely Imre (146083), Imre, Gergely, Tamas Korcsmaros, Dunai, Zsuzsanna A., Barna, Gabor, Rudolf Mihalik, Bauer, Pal I., Gabor Barna, Rudolf Mihalik (146097), Petak, Istvan, Zsuzsanna A. Dunai (144901), Korcsmaros, Tamas, Tamas Korcsmaros (146091)   +20 more
core   +2 more sources

Programmed cell death with a necrotic-like phenotype

Biomolecular Concepts, 2013
Programmed cell death is the process by which an individual cell in a multicellular organism commits cellular ‘suicide’ to provide a long-term benefit to the organism.
Morgan Michael J., Liu Zheng-gang
doaj   +1 more source

Programmed cell death-1 blockade in kidney carcinoma may induce eosinophilic granulomatosis with polyangiitis: a case report

BMC Pulmonary Medicine, 2021
Background Immune checkpoint inhibitors have potential applications in treating various cancers but are associated with immune-related adverse events, such as inflammation, in a wide range of organs; however, allergic inflammation caused by these agents ...
Masanori Harada, Hyogo Naoi, Kazuyo Yasuda, Yutaro Ito, Namio Kagoo, Tsutomu Kubota, Koshiro Ichijo, Eisuke Mochizuki, Masahiro Uehara, Shun Matsuura, Masaru Tsukui, Naoki Koshimizu   +11 more
doaj   +1 more source

The Underlying Mechanisms of Chinese Herbal Medicine-Induced Apoptotic Cell Death in Human Cancer

, 2020
The high incidence of cancer is a global burden. Cancer cells acquire immortality, which results in loss of control in cell proliferation and population expansion.
Feiyu Chen, Yibin Feng, Zhong, Z, Wang, N, Feng, Y, Tan, HYH, Ning Wang, Zhangfeng Zhong, Hor Yue Tan, Chen, F   +9 more
core   +1 more source

Gene trapping identifies transiently induced survival genes during programmed cell death [PDF]

, 2001
Background: The existence of a constitutively expressed machinery for death in individual cells has led to the notion that survival factors repress this machinery and, if such factors are unavailable, cells die by default.
Yang, Ji-Yeon, Hammann, Joanna, Wempe, Frank, Melchner, Harald von (Prof. Dr.)   +3 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega, Daniel J. Indelicato, Jeanette Parkes, Natia Esiashvili, Josué Hernández Benítez, Miriam Mikhail‐Lette, Olivera Cirajc Bjelac, Daniel Berger, Eva Ciurana, Yavuz Anacak, Lisbeth Cordero‐Mendez   +10 more
wiley   +1 more source