Results 31 to 40 of about 6,837,118 (237)

Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. [PDF]

PLoS ONE, 2013
Vertebrate genomes undergo epigenetic reprogramming during development and disease. Emerging evidence suggests that DNA methylation plays a key role in cell fate determination in the retina.
Karl J Wahlin, Raymond A Enke, John A Fuller, Giedrius Kalesnykas, Donald J Zack, Shannath L Merbs   +5 more
doaj   +1 more source

Hemotrophic mycoplasmas induce programmed cell death in red blood cells [PDF]

, 2011
Hemotrophic mycoplasmas (HM) are uncultivable bacteria found on and in the red blood cells (RBCs). The main clinical sign of HM infections is the hemolytic anemia. However, anemia-inducing pathogenesis has not been totally clarified. In this work we used
Groebel, K, Ritzmann, Mathias, Hoelzle, Katharina, Kilchling, T, Mathias Ritzmann, Ritzmann, M, Felder, Kathrin M., Hoelzle, K, Ludwig E. Hoelzle, Schiele, D, Katharina Hoelzle, Heinritzi, K, Daniela Schiele, Kilchling, Tim, Kathrin M. Felder, Tim Kilchling, Karl Heinritzi, Felder, K M, Katrin Groebel, Heinritzi, Karl, Groebel, Katrin, Schiele, Daniela, Hoelzle, Ludwig E, Hoelzle, Ludwig E.   +23 more
core   +1 more source

Nitric Oxide and Reactive Oxygen Species Do Not Elicit Hypersensitive Cell Death but Induce Apoptosis in the Adjacent Cells During the Defense Response of Oat

Molecular Plant-Microbe Interactions, 2004
Nitric oxide (NO) acts as a signaling molecule in many cellular responses in plants and animals. Oat plants (Avena sativa L.) evoke the hypersensitive response (HR), which shares morphological and biochemical features with mammalian apoptosis, such as ...
Yasuomi Tada, Tomoyo Mori, Takeshi Shinogi, Nan Yao, Satsuki Takahashi, Shigeyuki Betsuyaku, Masaru Sakamoto, Pyoyun Park, Hitoshi Nakayashiki, Yukio Tosa, Shigeyuki Mayama   +10 more
doaj   +1 more source

Transarterial Chemoembolization Combined With PD-1 Inhibitors Plus Lenvatinib Showed Improved Efficacy for Treatment of Unresectable Hepatocellular Carcinoma Compared With PD-1 Inhibitors Plus Lenvatinib

Technology in Cancer Research & Treatment, 2023
Background: Programmed cell death protein-1 inhibitors combined with lenvatinib have become a popular treatment option for patients with unresectable hepatocellular carcinoma.
Jinfeng Wang MM, Man Zhao MM, Guangjie Han MM, Xin Han MM, Jianfei Shi PhD, Lili Mi PhD, Ning Li BM, Xiaolei Yin MM, Xiaoling Duan PhD, Jiaojiao Hou MM, Fei Yin PhD   +10 more
doaj   +1 more source

Programmed Cell Death-1/Programmed Cell Death-1 Ligand as Prognostic Markers of Coronavirus Disease 2019 Severity

Cells, 2022
Current research proves that immune dysregulation is a common feature of coronavirus disease 2019 (COVID-19), and immune exhaustion is associated with increased disease mortality.
Paulina Niedźwiedzka-Rystwej, Adam Majchrzak, Bogusz Aksak-Wąs, Karol Serwin, Zenon Czajkowski, Ewelina Grywalska, Izabela Korona-Głowniak, Jacek Roliński, Miłosz Parczewski   +8 more
doaj   +1 more source

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death [PDF]

, 2006
Histolysis refers to a widespread disintegration of tissues that is morphologically distinct from apoptosis and often associated with the stimulation of autophagy. Here, we establish that a component of the apoptosome, and pivotal regulator of apoptosis,
Xiaodong Wang, John M. Abrams, Suganthi Chittaranjan, Gorski, Sharon M., Antony Rodriguez, Medved'ova, L, Wang, Xd, Rodriguez, Antony, Akdemir, Fatih, Farkas, Robert, Sharon M. Gorski, Lai Wang, Medved'ová, Lucia, Abrams, John M., Wang, Xiaodong, Sass, Miklós, Gabor Juhasz, Chittaranjan, Suganthi, Robert Farkaš, Abrams, Jm, Po Chen, Miklos Sass, Fatih Akdemir, Chen, Po, Lucia Medved'ová, Gorski, Sm, Juhász, Gábor, Wang, Lai   +27 more
core   +1 more source

Regulation of a Virus-Induced Lethal Disease in Tomato Revealed by LongSAGE Analysis

Molecular Plant-Microbe Interactions, 2007
Infection of Cucumber mosaic virus (CMV) and D satellite RNA (satRNA) in tomato plants induces rapid plant death, which has caused catastrophic crop losses.
Saeed Irian, Ping Xu, Xinbin Dai, Patrick X. Zhao, Marilyn J. Roossinck   +4 more
doaj   +1 more source

Programmed cell death in hepatic fibrosis: current and perspectives

Cell Death Discovery, 2023
The initiation, development and resolution of hepatic fibrosis are influenced by various cytokines, chemokines, damage-associated molecular patterns (DAMPs) and signaling pathways.
Ju-Lu Lu, Chuan-Xin Yu, Li-Jun Song
doaj   +1 more source

Development of a Lesion-Mimic Phenotype in a Transgenic Wheat Line Overexpressing Genes for Pathogenesis-Related (PR) Proteins Is Dependent on Salicylic Acid Concentration

Molecular Plant-Microbe Interactions, 2003
In the course of coexpressing genes for pathogenesis-related (PR) proteins for a class IV chitinase and an acidic glucanase in transgenic wheat plants, we regenerated a wheat line that developed necrotic lesions containing dead cells in the T2 and ...
Ajith Anand, Eric A. Schmelz, Subbaratnam Muthukrishnan   +2 more
doaj   +1 more source

Caspase inhibitors affect the kinetics and dimensions of tracheary elements in xylogenic Zinnia (Zinnia elegans) cell cultures [PDF]

, 2010
Background The xylem vascular system is composed of fused dead, hollow cells called tracheary elements (TEs) that originate through trans-differentiation of root and shoot cambium cells. TEs undergo autolysis as they differentiate and mature.
Elena T Iakimova, Ernst J Woltering, Qian Tian, Twumasi, P., Schel Jan HN, Emons, A.M.C., Wim van Ieperen, Olaf van Kooten, van Ieperen Wim, van Kooten, O., van Ieperen, W., Iakimova, E.T., van Kooten Olaf, Qian, T., Emons Anne, Schel, J.H.N., Peter Twumasi, Tian Qian, Iakimova Elena T, Woltering, E.J., Anne Emons, Kooten, O., van, Ieperen, W., van, Anne MieC Emons, Twumasi Peter, Woltering Ernst J, Jan HN Schel   +26 more
core   +1 more source