Gene trapping identifies transiently induced survival genes during programmed cell death [PDF]
, 2001 Background: The existence of a constitutively expressed machinery for death in individual cells has led to the notion that survival factors repress this machinery and, if such factors are unavailable, cells die by default.
Wempe, Frank +3 more
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BMC Pulmonary Medicine, 2021 Background Immune checkpoint inhibitors have potential applications in treating various cancers but are associated with immune-related adverse events, such as inflammation, in a wide range of organs; however, allergic inflammation caused by these agents ...
Masanori Harada +11 more
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Autophagy is activated and involved in cell death with participation of cathepsins during stress-induced microspore embryogenesis in barley [PDF]
, 2018 Microspores are reprogrammed towards embryogenesis by stress. Many microspores die after this stress, limiting the efficiency of microspore embryogenesis. Autophagy is a degradation pathway that plays critical roles in stress response and cell death.
Berenguer, Eduardo +4 more
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Programmed cell death with a necrotic-like phenotype
Biomolecular Concepts, 2013 Programmed cell death is the process by which an individual cell in a multicellular organism commits cellular ‘suicide’ to provide a long-term benefit to the organism.
Morgan Michael J., Liu Zheng-gang
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Programmed cell death in pathogenic fungi. [PDF]
, 2013 addresses: School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, UK. M.Ramsdale@exeter.ac.uktypes: Journal Article; Research Support, Non-U.S. Gov't; ReviewCopyright © 2008 Elsevier.
Ramsdale, M
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Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements [PDF]
, 2001 Many neurons die as the normal brain develops. How this is regulated and whether the mechanism involves neurotrophic molecules from target cells are unknown.
Asavaritikrai, P +3 more
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A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer. [PDF]
, 2015 Serous Ovarian Cancers (SOC) are frequently resistant to programmed cell death. However, here we describe that these programmed death-resistant cells are nonetheless sensitive to agents that modulate autophagy.
Bartakova, Alena +10 more
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Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death [PDF]
, 2006 Histolysis refers to a widespread disintegration of tissues that is morphologically distinct from apoptosis and often associated with the stimulation of autophagy. Here, we establish that a component of the apoptosome, and pivotal regulator of apoptosis,
Abrams, John M. +11 more
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PD-L1 Expression and Combined Status of PD-L1/PD-1–Positive Tumor Infiltrating Mononuclear Cell Density Predict Prognosis in Glioblastoma Patients [PDF]
Journal of Pathology and Translational Medicine, 2017 Background Programmed death ligand 1 (PD-L1) in tumor cells is known to promote immune escape of cancer by interacting with programmed cell death 1 (PD-1) in tumor infiltrating immune cells.
Jiheun Han, Yongkil Hong, Youn Soo Lee
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Main Pro-Apoptotic Member of BCL-2 Family Proteins-BAX [PDF]
, 2010 Programmed cell death (apoptosis) plays a vital role in the regulation of cellular homeostasis. Because of apoptosis fundamental importance, this process is highly regulated.
Kiliańska, Zofia, Żolnierczyk, Jolanta
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