Results 41 to 50 of about 1,266,471 (355)

Diversity and complexity of cell death: a historical review

Experimental and Molecular Medicine, 2023
Death is the inevitable fate of all living organisms, whether at the individual or cellular level. For a long time, cell death was believed to be an undesirable but unavoidable final outcome of nonfunctioning cells, as inflammation was inevitably ...
Wonyoung Park, Shibo Wei, Bo-Sung Kim, Bosung Kim, Sung-Jin Bae, Y. Chae, D. Ryu, Ki-Tae Ha   +7 more
semanticscholar   +1 more source

Programmed cell death-1 blockade in kidney carcinoma may induce eosinophilic granulomatosis with polyangiitis: a case report

BMC Pulmonary Medicine, 2021
Background Immune checkpoint inhibitors have potential applications in treating various cancers but are associated with immune-related adverse events, such as inflammation, in a wide range of organs; however, allergic inflammation caused by these agents ...
Masanori Harada, Hyogo Naoi, Kazuyo Yasuda, Yutaro Ito, Namio Kagoo, Tsutomu Kubota, Koshiro Ichijo, Eisuke Mochizuki, Masahiro Uehara, Shun Matsuura, Masaru Tsukui, Naoki Koshimizu   +11 more
doaj   +1 more source

Programmed cell death in pathogenic fungi. [PDF]

, 2013
addresses: School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, UK. M.Ramsdale@exeter.ac.uktypes: Journal Article; Research Support, Non-U.S. Gov't; ReviewCopyright © 2008 Elsevier.
Ramsdale, M
core   +1 more source

Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer.

Journal of Clinical Oncology, 2018
PURPOSE Treatment with programmed cell death-1 or programmed death ligand 1 (PD-(L)1) inhibitors is now standard therapy for patients with lung cancer. The immunosuppressive effect of corticosteroids may reduce efficacy of PD-(L)1 blockade.
K. Arbour, L. Mezquita, N. Long, H. Rizvi, E. Auclin, A. Ni, G. Martínez-Bernal, R. Ferrara, W. Lai, L. Hendriks, J. Sabari, C. Caramella, A. Plodkowski, D. Halpenny, J. Chaft, D. Planchard, Gregory Riely, B. Besse, M. Hellmann   +18 more
semanticscholar   +1 more source

Programmed cell death with a necrotic-like phenotype

Biomolecular Concepts, 2013
Programmed cell death is the process by which an individual cell in a multicellular organism commits cellular ‘suicide’ to provide a long-term benefit to the organism.
Morgan Michael J., Liu Zheng-gang
doaj   +1 more source

Programmed cell death pathways in hearing loss: A review of apoptosis, autophagy and programmed necrosis

Cell Proliferation, 2020
Programmed cell death (PCD)—apoptosis, autophagy and programmed necrosis—is any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing ...
Junhao Wu, Jing Ye, W. Kong, Shouyue Zhang, Yun Zheng   +4 more
semanticscholar   +1 more source

Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons [PDF]

, 2014
Mitochondrial dysfunction is the underlying cause of many neurological disorders, including peripheral neuropathies. Mitochondria rely on a proton gradient to generate ATP and interfering with electron transport chain function can lead to the deleterious
DiAntonio, Aaron, Milbrandt, Jeffrey, Summers, Daniel W   +2 more
core   +2 more sources

Research progress on morphology and mechanism of programmed cell death

Cell Death and Disease
Programmed cell death (PCD) is a basic process of life that is closely related to the growth, development, aging and disease of organisms and is one of the hotspots of life science research today.
Yao Chen, Xiaohua Li, Minfeng Yang, Song-Bai Liu   +3 more
semanticscholar   +1 more source

Programmed cell death protein 1 and programmed death ligand 1 expression in neuroendocrine carcinomas of the urinary bladder

Polish Journal of Pathology, 2021
Neuroendocrine carcinomas (NECs) of the urinary bladder are rare and aggressive, without an effective treatment approach. Immune checkpoint inhibitor agents targeting the interaction of programmed cell death protein 1 (PD-1) and programmed death ligand 1
Arbil Acikalin, Emine Bagir, Merve Inceman, Mutlu Deger, Seyda Erdogan   +4 more
doaj   +1 more source

Prediction Of Cancer Possibility By Pattern Recognition And Statistical Study Of Expression Of Gene Level Of Cancer Cells [PDF]

, 2011
The activity of the p53 tumor-suppressor protein has a key role in controlling both cancer and aging: under activity encourages the growth of cancer, and over activity can accelerate the aging process.
Devang Odedra, Medhavi Mallick
core   +2 more sources