Results 41 to 50 of about 572,695 (365)

PD-L1 Expression and Combined Status of PD-L1/PD-1–Positive Tumor Infiltrating Mononuclear Cell Density Predict Prognosis in Glioblastoma Patients [PDF]

open access: yesJournal of Pathology and Translational Medicine, 2017
Background Programmed death ligand 1 (PD-L1) in tumor cells is known to promote immune escape of cancer by interacting with programmed cell death 1 (PD-1) in tumor infiltrating immune cells.
Jiheun Han, Yongkil Hong, Youn Soo Lee
doaj   +1 more source

Using biophotonics to study signaling mechanisms in a single living cell [PDF]

open access: yesIntl J Mod Phys B, 21 (23/24):4091-4103, 2007, 2014
To illustrate the power of the biophysical approach in solving important problems in life science, I present here one of our current research projects as an example. We have developed special biophotonic techniques to study the dynamic properties of signaling proteins in a single living cell.
arxiv   +1 more source

Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae [PDF]

open access: yes, 2005
Prova tipográfica (In Press)During the last years, several reports described an apoptosis-like programmed cell death process in yeast in response to different environmental aggressions.
Baker   +42 more
core   +1 more source

Cell Death

open access: yes, 2014
Recent studies in Drosophila, Hydra, planarians, zebrafish, mice, indicate that cell death can open paths to regeneration in adult animals. Indeed injury can induce cell death, itself triggering regeneration following an immediate instructive mechanism, whereby the dying cells release signals that induce cellular responses over short and/or long-range ...
Silke Reiter   +3 more
openaire   +6 more sources

Programmed Cell Death in Liver Fibrosis

open access: yesJournal of Inflammation Research, 2023
Ruoyu Gao,1 Haiying Tang,2 Jingwei Mao1 1Department of Gastroenterology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, First Affiliated Hospital ...
Gao R, Tang H, Mao J
doaj  

Regulation of programmed cell death by Brd4

open access: yesCell Death and Disease, 2022
Epigenetic factor Brd4 has emerged as a key regulator of cancer cell proliferation. Targeted inhibition of Brd4 suppresses growth and induces apoptosis of various cancer cells.
Jinfeng Hu   +4 more
doaj   +1 more source

Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells [PDF]

open access: yesCPT: Pharmacometrics & Systems Pharmacology 4, no. 4 (2015): 263-272, 2013
Autophagy is a conserved biological stress response in mammalian cells that is responsible for clearing damaged proteins and organelles from the cytoplasm and recycling their contents via the lysosomal pathway. In cases of mild stress, autophagy acts as a survival mechanism, while in cases of severe stress cells may switch to programmed cell death ...
arxiv   +1 more source

Programmed cell death in pathogenic fungi. [PDF]

open access: yes, 2013
addresses: School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, UK. M.Ramsdale@exeter.ac.uktypes: Journal Article; Research Support, Non-U.S. Gov't; ReviewCopyright © 2008 Elsevier.
Ramsdale, M
core   +1 more source

Morphological changes and patterns of ecdysone receptor B1 immunolocalization in the anterior silk gland undergoing programmed cell death in the silkworm, Bombyx mori [PDF]

open access: yes, 2009
SummaryThe silk gland is a specific larval tissue of Lepidopteran insects and begins to degenerate shortly before pupation. The steroid hormone ecdysone triggers the stage specific programmed cell death of the anterior silk glands during metamorphosis in
Ebru Goncu   +49 more
core   +1 more source

Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein ligand-1

open access: yesChinese Medical Journal, 2020
. Historically, breast cancer has been regarded as an immunogenic “cold” tumor. However, the discovery of immune checkpoint inhibitors has made immunotherapy becoming an emerging new treatment modality for breast cancer.
Jing Zhao, Jian Huang, Qiang Shi
doaj   +1 more source

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