Results 41 to 50 of about 1,245,864 (402)

Programmed cell death protein 1 and programmed death ligand 1 expression in neuroendocrine carcinomas of the urinary bladder

Polish Journal of Pathology, 2021
Neuroendocrine carcinomas (NECs) of the urinary bladder are rare and aggressive, without an effective treatment approach. Immune checkpoint inhibitor agents targeting the interaction of programmed cell death protein 1 (PD-1) and programmed death ligand 1
Arbil Acikalin, Emine Bagir, Merve Inceman, Mutlu Deger, Seyda Erdogan   +4 more
doaj   +1 more source

Diversity and complexity of cell death: a historical review

Experimental and Molecular Medicine, 2023
Death is the inevitable fate of all living organisms, whether at the individual or cellular level. For a long time, cell death was believed to be an undesirable but unavoidable final outcome of nonfunctioning cells, as inflammation was inevitably ...
Wonyoung Park, Shibo Wei, Bo-Sung Kim, Bosung Kim, Sung-Jin Bae, Y. Chae, D. Ryu, Ki-Tae Ha   +7 more
semanticscholar   +1 more source

Programmed cell death in the skin

The International Journal of Developmental Biology, 2015
Differently from the other cells of the body, epidermal cells of the skin undergo a specific programmed cell death form named cornification. Many events take part to control this process, which has been described as a terminal differentiation program.
Costanzo, Antonio, Fausti, Francesca, Spallone, Giulia, MORETTI, FRANCESCA, NARCISI, ALESSANDRA, BOTTI, ELISABETTA   +5 more
openaire   +5 more sources

Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae [PDF]

, 2005
Prova tipográfica (In Press)During the last years, several reports described an apoptosis-like programmed cell death process in yeast in response to different environmental aggressions.
Baker, Balzan, Brown, Chan, Del Carratore, Dumont, Edwards, Fahrenkrog, Fannjiang, Galvez, Goldstein, Granot, Haugland, Heeren, Herker, Hoover, Huh, Laun, Liao, Ligr, Liu, Ludovico, Ludovico, Ludovico, Ludovico, Madeo, Madeo, Madeo, Madeo, Manon, Matthews, Mockridge, Morales, Pozniakovsky, Reilly, Severin, Silva, Vieira, Wadskog, Wissing, Wright, Wysocki, Yamaki   +42 more
core   +1 more source

Programmed cell death in pathogenic fungi. [PDF]

, 2013
addresses: School of Biosciences, University of Exeter, Geoffrey Pope Building, Exeter, UK. M.Ramsdale@exeter.ac.uktypes: Journal Article; Research Support, Non-U.S. Gov't; ReviewCopyright © 2008 Elsevier.
Ramsdale, M
core   +1 more source

The role of Eag and HERG channels in cell proliferation and apoptotic cell death in SK-OV-3 ovarian cancer cell line. [PDF]

, 2011
The voltage gated potassium (K+) channels Eag and HERG have been implicated in the pathogenesis of various cancers, through association with cell cycle changes and programmed cell death.
Anish Bali, Asher, Viren, Averil Warren, Heidi Sowter, Raheela Khan, Robert Shaw, Viren Asher   +6 more
core   +5 more sources

Programmed cell death-1 blockade in kidney carcinoma may induce eosinophilic granulomatosis with polyangiitis: a case report

BMC Pulmonary Medicine, 2021
Background Immune checkpoint inhibitors have potential applications in treating various cancers but are associated with immune-related adverse events, such as inflammation, in a wide range of organs; however, allergic inflammation caused by these agents ...
Masanori Harada, Hyogo Naoi, Kazuyo Yasuda, Yutaro Ito, Namio Kagoo, Tsutomu Kubota, Koshiro Ichijo, Eisuke Mochizuki, Masahiro Uehara, Shun Matsuura, Masaru Tsukui, Naoki Koshimizu   +11 more
doaj   +1 more source

Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer.

Journal of Clinical Oncology, 2018
PURPOSE Treatment with programmed cell death-1 or programmed death ligand 1 (PD-(L)1) inhibitors is now standard therapy for patients with lung cancer. The immunosuppressive effect of corticosteroids may reduce efficacy of PD-(L)1 blockade.
K. Arbour, L. Mezquita, N. Long, H. Rizvi, E. Auclin, A. Ni, G. Martínez-Bernal, R. Ferrara, W. Lai, L. Hendriks, J. Sabari, C. Caramella, A. Plodkowski, D. Halpenny, J. Chaft, D. Planchard, Gregory Riely, B. Besse, M. Hellmann   +18 more
semanticscholar   +1 more source

Programmed cell death pathways in hearing loss: A review of apoptosis, autophagy and programmed necrosis

Cell Proliferation, 2020
Programmed cell death (PCD)—apoptosis, autophagy and programmed necrosis—is any pathological form of cell death mediated by intracellular processes. Ototoxic drugs, ageing and noise exposure are some common pathogenic factors of sensorineural hearing ...
Junhao Wu, Jing Ye, W. Kong, Shouyue Zhang, Yun Zheng   +4 more
semanticscholar   +1 more source

Both the Caspase CSP-1 and a Caspase-Independent Pathway Promote Programmed Cell Death in Parallel to the Canonical Pathway for Apoptosis in Caenorhabditis elegans [PDF]

, 2012
Caspases are cysteine proteases that can drive apoptosis in metazoans and have critical functions in the elimination of cells during development, the maintenance of tissue homeostasis, and responses to cellular damage. Although a growing body of research
A Cauwels, A Degterev, A Gartner, A Raj, AH Wyllie, AM Chinnaiyan, B Conradt, B Pinan-Lucarre, B Schumacher, BT Hyman, D Xue, D Xue, Daniel P. Denning, DJ Dwyer, DJ Hoeppner, DP Denning, DT Harris, E Arama, E Pourkarimi, EC Andersen, EH Cheng, EM Hedgecock, ES Blum, F Chen, F Madeo, F Simmer, H. Robert Horvitz, HC Chang, Hermann Steller, HM Ellis, HT Schwartz, J Yuan, J Yuan, JE Sulston, JE Sulston, JF Kerr, JM Kinchen, JY Yuan, K Xu, M Darland-Ransom, MC Abraham, MC Abraham, MO Hengartner, MO Hengartner, NA Thornberry, PW Reddien, RA Lockshin, RE Ellis, S Brenner, S Harbinder, S Qi, S Seshagiri, S Shaham, S Shaham, S Shaham, SA Susin, T Hirose, TL Gumienny, V Venegas, VA Fadok, Victoria Hatch, X Geng, X Geng, X Wang, X Yang, Z Zhou   +65 more
core   +4 more sources