Results 61 to 70 of about 572,695 (365)
Haematologica, 2009 Background Programmed cell death has been traditionally related with caspase activation. However, it is now accepted that caspase-independent forms of programmed cell death also regulate cell death.
Sandrine Barbier +12 more
doaj +1 more source
Alternative cell death pathways and cell metabolism [PDF]
, 2013 While necroptosis has for long been viewed as an accidental mode of cell death triggered by physical or chemical damage, it has become clear over the last years that necroptosis can also represent a programmed form of cell death in mammalian cells.
Fulda, Simone
core +2 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Programmed cell death proteins and chronic leukemia [PDF]
Archives of Biological Sciences, 2011 Apoptosis or programmed cell death is a genetically regulated process of cellular suicide. Apoptosis has been implicated in a wide range of pathological conditions, and mutations in apoptotic genes play important roles in the process of malignant ...
Brajušković G. +3 more
doaj +1 more source
Non-Apoptotic Programmed Cell Death in Thyroid Diseases
Pharmaceuticals, 2022 Thyroid disorders are among the most common endocrinological conditions. As the prevalence of thyroid diseases increases annually, the exploration of thyroid disease mechanisms and the development of treatments are also gradually improving.
Feihong Ji, Xinguang Qiu
doaj +1 more source
Apoptosis - Programmed Cell Death [PDF]
, 2003 Tijekom evolucije višestanični organizmi uspjeli su razviti različite mehanizme zaštite od djelovanja štetnih utjecaja iz okoline. Apoptoza ili “programirana smrt stanice” jedan je od tih mehanizama kojim stanica aktivno uz utrošak energije i sintezu ...
Vilim Žlender
core +1 more source
Targeting apoptosis signaling in pancreatic cancer [PDF]
, 2011 The ability to escape apoptosis or programmed cell death is a hallmark of human cancers, for example pancreatic cancer. This can promote tumorigenesis, since too little cell death by apoptosis disturbs tissue homeostasis.
Fulda, Simone
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Assessment of programmed cell death 1 and its programmed cell death ligand 1 levels in vitiligo
Journal of the Egyptian Women’s Dermatologic SocietyBackground Programmed cell death 1 (PD-1) is a cell surface protein that serves as an immune checkpoint in conjunction with its two ligands, PD-L1 and PD-L2.
Hanan R. Nada +5 more
doaj +1 more source
Programmed Cell Death in Health and Disease
Cells, 2021 Programmed cell death is a conserved evolutionary process of cell suicide that is central to the development and integrity of eukaryotic organisms [...]
Lara Gibellini, Loredana Moro
doaj +1 more source