Results 11 to 20 of about 272,392 (299)

Research progress on programmed death receptor 1/ ligand 1 inhibitor in immunotherapy of head and neck squamous cell carcinoma

open access: yes口腔疾病防治, 2021
Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumor that seriously threatens human health and life. With increasing studies on the mechanism of tumor immune escape, programmed death receptor 1 (PD-1) and programmed death ligand ...
ZENG Fei   +6 more
doaj   +1 more source

Multiple lung cancers including squamous cell carcinoma with strong PD-L1 expression and adenocarcinoma with EGFR exon 19 deletion: A case report

open access: yesRespiratory Medicine Case Reports, 2020
We herein report a non-smoking 81-year-old man with advanced synchronous multiple primary lung cancers (SMPLC), containing squamous cell carcinoma with strong programmed death-ligand 1 expression in the middle lobe and adenocarcinoma with epidermal ...
Hirokazu Tokuyasu   +5 more
doaj   +1 more source

Dual Vascular Endothelial Growth Factor Receptor and Fibroblast Growth Factor Receptor Inhibition Elicits Antitumor Immunity and Enhances Programmed Cell Death-1 Checkpoint Blockade in Hepatocellular Carcinoma

open access: yesLiver Cancer, 2020
Background and Aims: Combining anti-angiogenic therapy with immune checkpoint blockade with anti-programmed cell death-1 (PD-1) antibodies is a promising treatment for hepatocellular carcinoma (HCC).
Hai-Jing Deng   +14 more
semanticscholar   +1 more source

Update on the anti‐programmed cell death‐1 receptor antibodies in advanced cutaneous squamous‐cell carcinoma

open access: yesDermatologic Therapy, 2020
Regarding the rising incidence and the not negligible mortality, the treatment of cutaneous squamous‐cell carcinoma (cSCC) has a high clinical relevance.
M. Benzaquen
semanticscholar   +1 more source

The journey of dostarlimab: a successful weapon for cancer treatment

open access: yesExploration of Medicine, 2022
In a number of malignancies, new immuno-oncology therapies that focus on the programmed cell death 1 (PD-1) have improvised the patient condition along with a positive aftereffect. Monoclonal antibodies (mAbs) directed against PD-1 and its ligand (PD-L1),
Rouchan Ali   +2 more
doaj   +1 more source

Burgeoning Exploration of the Role of Natural Killer Cells in Anti-PD-1/PD-L1 Therapy

open access: yesFrontiers in Immunology, 2022
Antibodies targeting programmed death receptor-1 (PD-1)/programmed death ligand-1 (PD-L1) have been considered breakthrough therapies for a variety of solid and hematological malignancies.
Rilan Bai, Jiuwei Cui
doaj   +1 more source

Changes and correlations of T-cell coinhibitory molecule programmed death-1 and interferon-γ in pediatric immune thrombocytopenia [PDF]

open access: yesClinical and Experimental Pediatrics, 2023
Background Immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by abnormalities of T cells subsets. Programmed death-1 (PD-1) is a co-signaling inhibitory molecule in T cells that is involved in many autoimmune diseases. Purpose
Fady Mohamed El-Gendy   +3 more
doaj   +1 more source

The Role of Programmed Cell Death Receptor 1 in Lung Cancer [PDF]

open access: yesIn Vivo, 2022
Lung cancer is the most common cancer worldwide. Cancer immunotherapy is the activation of the immune system against cancer. The latest method of immunotherapy involves immune checkpoint inhibitors. Increased levels of programmed death ligand 1 (PD-L1) expression were observed on non-small-cell lung cancer.
Dumitru Cristinel, Badiu   +5 more
openaire   +2 more sources

A High Programmed Cell Death Protein 1 Hormone Receptor Score on Skin Biopsy is Associated with Sézary Syndrome Diagnosis: A Study of 91 Patients with Erythroderma

open access: yesActa Dermato-Venereologica, 2022
Erythroderma is challenging to diagnose. The aim of this single-centre retrospective study was to identify factors that can be used to improve the diagnosis of erythroderma.
Camille Luherne   +10 more
doaj   +1 more source

Programmed Cell Death in Sepsis Associated Acute Kidney Injury

open access: yesFrontiers in Medicine, 2022
Sepsis-associated acute kidney injury (SA-AKI) is common in patients with severe sepsis, and has a high incidence rate and high mortality rate in ICU patients. Most patients progress to AKI before drug treatment is initiated.
Zhifen Wu   +5 more
doaj   +1 more source

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