Results 201 to 210 of about 180,865 (263)

Elucidating shared genes and pathways in programmed cell death with necrotizing enterocolitis: insights into novel therapeutic targets and glutathione. [PDF]

open access: yesTransl Pediatr
Zou P   +15 more
europepmc   +1 more source

Alcohol induces programmed death receptor-1 and programmed death-ligand-1 differentially in neuroimmune cells

Alcohol, 2020
Engagement of programmed death-1 (PD-1) receptor by its ligands (PD-L1/PD-L2) in activated immune cells is known to be involved in inflammatory neurological disease via a co-inhibitory signal pathway. Interaction of PD-1/PD-L1 is believed to occur only in activated neuroimmune cells because there are undetectable levels of PD-1/PD-L1 in normal ...
Vikas Mishra   +4 more
openaire   +2 more sources

[Development of programmed death receptor-1 and programmed death receptor-1 ligand in oral squamous cell carcinoma].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2020
Oral squamous cell carcinoma (OSCC) is a common malignant tumor in the oral and maxillofacial region. At present, the treatment of OSCC is mainly based on surgical oriented comprehensive sequence therapy, especially the triple therapy of surgery, radiotherapy, and chemotherapy. However, the overall five-year survival rate is relatively low.
Zhi-Hong, Chen, Ya-Dong, Wu
openaire   +1 more source

The p53/IGF-1 receptor axis in the regulation of programmed cell death

Endocrine, 1997
The loss or functional inactivation of tumor suppressor genes appears to be one of the most fundamental genetic mechanisms of tumorigenesis, and rational insights into the signaling pathways of tumor suppressor genes have emerged as a successful strategy of identifying novel drug discovery targets downstream of the tumor suppressor protein itself ...
M, Neuberg   +3 more
openaire   +2 more sources

Programmed cell death 1 (PD-1) receptor and programmed death ligand 1 (PD-L1) gene expression in primary breast cancer

Breast Cancer Research and Treatment, 2021
The interaction of the programmed cell death 1 (PD-1) receptor on tumor-infiltrating lymphocytes with programmed death ligand 1 (PD-L1) on tumor cells downregulates anti-tumor immunity. This study evaluated associations between PD-1 and PD-L1 expression in primary breast cancer, clinical characteristics, and patient outcomes.Microarray data from the ...
Neelima Vidula   +2 more
openaire   +2 more sources

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