Results 11 to 20 of about 35,471,860 (258)

Malaria ookinetes exhibit multiple markers for apoptosis-like programmed cell death in vitro. [PDF]

, 2009
Background: A wide range of unicellular eukaryotes have now been shown to undergo a form of programmed cell death (PCD) that resembles apoptosis; exhibiting morphological and, in some cases, biochemical markers typical of metazoans. However, reports that
Arambage, S.C., Karen M Grant, Grant, Karen M., Pardo, Ian, Hilary Hurd, Grant, K.M., Hurd, Hilary, Ranford-Cartwright, Lisa, Ian Pardo, Lisa Ranford-Cartwright, Hurd, H., Pardo, I., Shashini C Arambage, Arambage, Shashini C., Ranford-Cartwright, L.C., Arambage Shashini C, Ranford-Cartwright Lisa, Pardo Ian, Grant Karen M, Hurd Hilary   +19 more
core   +5 more sources

Bloodstream form trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes [PDF]

, 2006
Trypanosoma brucei possesses five metacaspase genes. Of these, MCA2 and MCA3 are expressed only in the mammalian bloodstream form of the parasite, whereas MCA5 is expressed also in the insect procyclic form.
Appleton, Paul, Ambit, Audrey, Helms, Matthew J., Tetley, Laurence, Mottram, Jeremy C., Coombs, Graham H.   +5 more
core   +4 more sources

Programmed cell death in type II neuroblast lineages is required for central complex development in the Drosophila brain [PDF]

, 2012
Background: The number of neurons generated by neural stem cells is dependent upon the regulation of cell proliferation and by programmed cell death.
Heinrich Reichert, Reichert, Heinrich, Yanrui Jiang, Reichert Heinrich, Jiang Yanrui, Jiang, Yanrui   +5 more
core   +1 more source

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells [PDF]

, 2012
For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner.
Gabor Barna (146087), Pal I Bauer, Istvan Petak, Mihalik, Rudolf, Zsuzsanna A Dunai, Gergely Imre, Istvan Petak (5648680), Pal I. Bauer (144904), Gergely Imre (146083), Imre, Gergely, Tamas Korcsmaros, Dunai, Zsuzsanna A., Barna, Gabor, Rudolf Mihalik, Bauer, Pal I., Gabor Barna, Rudolf Mihalik (146097), Petak, Istvan, Zsuzsanna A. Dunai (144901), Korcsmaros, Tamas, Tamas Korcsmaros (146091)   +20 more
core   +2 more sources

Burgeoning Exploration of the Role of Natural Killer Cells in Anti-PD-1/PD-L1 Therapy

Frontiers in Immunology, 2022
Antibodies targeting programmed death receptor-1 (PD-1)/programmed death ligand-1 (PD-L1) have been considered breakthrough therapies for a variety of solid and hematological malignancies.
Rilan Bai, Jiuwei Cui
doaj   +1 more source

Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites [PDF]

, 2011
Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Sarah E Reece, Szymon Kaczanowski, Reece, Sarah E., Kaczanowski Szymon, Kaczanowski, S., Reece, S.E., Reece Sarah E, Mohammed Sajid, Sajid Mohammed, Sajid, M., Reece, Sarah, Sajid, Mohammed, Kaczanowski, Szymon   +12 more
core   +1 more source

A High Programmed Cell Death Protein 1 Hormone Receptor Score on Skin Biopsy is Associated with Sézary Syndrome Diagnosis: A Study of 91 Patients with Erythroderma

Acta Dermato-Venereologica, 2022
Erythroderma is challenging to diagnose. The aim of this single-centre retrospective study was to identify factors that can be used to improve the diagnosis of erythroderma.
Camille Luherne, Sarah Menguy, Thomas Ferte, Marie Beylot-Barry, Julien Seneschal, Brigitte Milpied, Jean-Philippe Vial, Audrey Gros, Samuel Amintas, Béatrice Vergier, Anne Pham-Ledard   +10 more
doaj   +1 more source

Programmed Cell Death in Sepsis Associated Acute Kidney Injury

Frontiers in Medicine, 2022
Sepsis-associated acute kidney injury (SA-AKI) is common in patients with severe sepsis, and has a high incidence rate and high mortality rate in ICU patients. Most patients progress to AKI before drug treatment is initiated.
Zhifen Wu, Junhui Deng, Hongwen Zhou, Wei Tan, Lirong Lin, Jurong Yang   +5 more
doaj   +1 more source

Sulforaphane enhances the antitumor response of chimeric antigen receptor T cells by regulating PD-1/PD-L1 pathway

BMC Medicine, 2021
Background Chimeric antigen receptor T (CAR-T) cell therapy has limited effects in the treatment of solid tumors. Sulforaphane (SFN) is known to play an important role in inhibiting tumor growth, but its effect on CAR-T cells remains unclear. The goal of
Chunyi Shen, Zhen Zhang, Yonggui Tian, Feng Li, Lingxiao Zhou, Wenyi Jiang, Li Yang, Bin Zhang, Liping Wang, Yi Zhang   +9 more
doaj   +1 more source

The role of PD-1 signaling in health and immune-related diseases

Frontiers in Immunology, 2023
Programmed cell death 1 receptor (PD-1) and its ligands constitute an inhibitory pathway to mediate the mechanism of immune tolerance and provide immune homeostasis.
Ru-Yue Chen, Yun Zhu, Yun-Yan Shen, Qin-Ying Xu, Han-Yun Tang, Ning-Xun Cui, Lu Jiang, Xiao-Mei Dai, Wei-Qing Chen, Qiang Lin, Xiao-Zhong Li   +10 more
doaj   +1 more source