Results 31 to 40 of about 381,028 (332)

A Statecharts-Based Approach for WSN Application Development

Journal of Sensor and Actuator Networks, 2020
Wireless Sensor Network (WSN) software development challenges developers in two main ways: through system programming, which requires expertise in hardware and network management; and application programming, which requires domain-specific knowledge ...
Ismo Hakala, Xinyu Tan
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Low-Code Mixed Reality Programming Framework for Collaborative Robots: From Operator Intent to Executable Trajectories

Robotics
Efficient and intuitive programming strategies are essential for enabling robots to adapt to small-batch, high-mix production scenarios. Mixed reality (MR) and programming by demonstration (PbD) have shown great potential to lower the programming barrier
Ziyang Wang, Zhihai Li, Hongpeng Yu, Duotao Pan, Songjie Peng, Shenlin Liu   +5 more
doaj   +1 more source

Alternation in Quantum Programming: From Superposition of Data to Superposition of Programs [PDF]

, 2014
We extract a novel quantum programming paradigm - superposition of programs - from the design idea of a popular class of quantum algorithms, namely quantum walk-based algorithms.
Feng, Yuan, Ying, Mingsheng, Yu, Nengkun
core  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Foundations of Total Functional Data-Flow Programming [PDF]

Electronic Proceedings in Theoretical Computer Science, 2014
The field of declarative stream programming (discrete time, clocked synchronous, modular, data-centric) is divided between the data-flow graph paradigm favored by domain experts, and the functional reactive paradigm favored by academics.
Baltasar Trancón y Widemann, Markus Lepper   +1 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Economic modelling using constraint logic programming [PDF]

, 1996
This paper investigates the use of constraint logic programming (CLP) in economic modelling through the design and implementation of two economic models.
Donovan, N, Gilbert, D
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source