Results 31 to 40 of about 380,452 (284)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Alternation in Quantum Programming: From Superposition of Data to Superposition of Programs [PDF]
, 2014 We extract a novel quantum programming paradigm - superposition of programs - from the design idea of a popular class of quantum algorithms, namely quantum walk-based algorithms.
Feng, Yuan, Ying, Mingsheng, Yu, Nengkun
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
RoboticsEfficient and intuitive programming strategies are essential for enabling robots to adapt to small-batch, high-mix production scenarios. Mixed reality (MR) and programming by demonstration (PbD) have shown great potential to lower the programming barrier
Ziyang Wang +5 more
doaj +1 more source
Foundations of Total Functional Data-Flow Programming [PDF]
Electronic Proceedings in Theoretical Computer Science, 2014 The field of declarative stream programming (discrete time, clocked synchronous, modular, data-centric) is divided between the data-flow graph paradigm favored by domain experts, and the functional reactive paradigm favored by academics.
Baltasar Trancón y Widemann +1 more
doaj +1 more source
Economic modelling using constraint logic programming [PDF]
, 1996 This paper investigates the use of constraint logic programming (CLP) in economic modelling through the design and implementation of two economic models.
Donovan, N, Gilbert, D
core
Kickstarting Choreographic Programming
, 2015 We present an overview of some recent efforts aimed at the development of Choreographic Programming, a programming paradigm for the production of concurrent software that is guaranteed to be correct by construction from global descriptions of ...
Montesi, Fabrizio
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A Visual Programming Paradigm for Abstract Deep Learning Model Development
, 2019 Deep learning is one of the fastest growing technologies in computer science with a plethora of applications. But this unprecedented growth has so far been limited to the consumption of deep learning experts.
Aralikatte, Rahul +5 more
core +1 more source