Results 51 to 60 of about 37,638 (261)
Reachability under Contextual Locking [PDF]
Logical Methods in Computer Science, 2013 The pairwise reachability problem for a multi-threaded program asks, given control locations in two threads, whether they can be simultaneously reached in an execution of the program.
Remi Bonnet +3 more
doaj +1 more source
Programming with Multiple Paradigms in Lua [PDF]
, 2010 Lua is a scripting language used in many industrial applications, with an emphasis on embedded systems and games. Two key points in the design of the language that led to its widely adoption are flexibility and small size. To achieve these two conflicting goals, the design emphasizes the use of few but powerful mechanisms, such as first-class functions,
openaire +1 more source
International Journal of Software Innovation, 2022 Out of the four main programming paradigms, it is widely considered that functional programming is the most promising. The programming languages that implement the functional paradigm generally do so either in a pure manner, such as Haskell, or by providing a multi-paradigm programming solution, such as most Lisp dialects, in order to allow side ...
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Defeasible logic programming: language definition, operational semantics, and parallelism
Journal of Computer Science and Technology, 2001 This thesis defines Defeasible Logic Programming and provides a concrete specification of this new language through its operational semantics. Defeasible Logic Programming, or DeLP for short, has been defined based on the Logic Programming paradigm and ...
Alejandro Javier García
doaj
Migrating from Developing Asynchronous Multi-Threading Programs to Reactive Programs in Java
Applied SciencesModern software application development imposes standards regarding high performance, scalability, and minimal system latency. Multi-threading asynchronous programming is one of the standard solutions proposed by the industry for achieving such ...
Andrei Zbarcea, Cătălin Tudose
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source