Results 51 to 60 of about 383,659 (283)

Foundations of Total Functional Data-Flow Programming [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
The field of declarative stream programming (discrete time, clocked synchronous, modular, data-centric) is divided between the data-flow graph paradigm favored by domain experts, and the functional reactive paradigm favored by academics.
Baltasar Trancón y Widemann   +1 more
doaj   +1 more source

The KB paradigm and its application to interactive configuration

open access: yes, 2016
The knowledge base paradigm aims to express domain knowledge in a rich formal language, and to use this domain knowledge as a knowledge base to solve various problems and tasks that arise in the domain by applying multiple forms of inference.
B Bogaerts   +16 more
core   +1 more source

Concepts and Paradigms for Neuromorphic Programming

open access: yesCoRR, 2023
The value of neuromorphic computers depends crucially on our ability to program them for relevant tasks. Currently, neuromorphic computers are mostly limited to machine learning methods adapted from deep learning. However, neuromorphic computers have potential far beyond deep learning if we can only make use of their computational properties to harness
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Graph Rewriting Visual Language for Database Programming [PDF]

open access: yes, 1997
Textual database programming languages are computationally complete, but have the disadvantage of giving the user a non-intuitive view of the database information that is being manipulated.
King, P.J.H., Rodgers, Peter
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ScaFi: A Scala DSL and Toolkit for Aggregate Programming

open access: yesSoftwareX, 2022
Supported by current socio-scientific trends, programming the global behaviour of whole computational collectives makes for great opportunities, but also significant challenges.
Roberto Casadei   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Parallel Plug-In Programming Paradigm [PDF]

open access: yes, 2006
Software component architectures allow assembly of applications from individual software modules based on clearly defined programming interfaces, thus improving the reuse of existing solutions and simplifying application development. Furthermore, the plug-in programming paradigm additionally enables runtime reconfigurability, making it possible to ...
Ronald Baumann   +2 more
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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