Results 71 to 80 of about 383,659 (283)

Definitive programming : a paradigm for exploratory programming [PDF]

open access: yes, 2022
Exploratory software development is a method that applies to the development of programs whose requirement is initially unclear. In such a context, it is only through prototyping and experimenting on the prototypes that the requirement can be fully developed. A good exploratory software development method must have a short development cycle.
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Economic modelling using constraint logic programming [PDF]

open access: yes, 1996
This paper investigates the use of constraint logic programming (CLP) in economic modelling through the design and implementation of two economic models.
Donovan, N, Gilbert, D
core  

Cinnamons: A Computation Model Underlying Control Network Programming

open access: yes, 2017
We give the easily recognizable name "cinnamon" and "cinnamon programming" to a new computation model intended to form a theoretical foundation for Control Network Programming (CNP).
Kratchanov, Kostadin
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Migrating from Developing Asynchronous Multi-Threading Programs to Reactive Programs in Java

open access: yesApplied Sciences
Modern software application development imposes standards regarding high performance, scalability, and minimal system latency. Multi-threading asynchronous programming is one of the standard solutions proposed by the industry for achieving such ...
Andrei Zbarcea, Cătălin Tudose
doaj   +1 more source

Logic Programming for Describing and Solving Planning Problems

open access: yes, 2000
A logic programming paradigm which expresses solutions to problems as stable models has recently been promoted as a declarative approach to solving various combinatorial and search problems, including planning problems.
Bruynooghe, Maurice
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Defeasible logic programming: language definition, operational semantics, and parallelism

open access: yesJournal of Computer Science and Technology, 2001
This thesis defines Defeasible Logic Programming and provides a concrete specification of this new language through its operational semantics. Defeasible Logic Programming, or DeLP for short, has been defined based on the Logic Programming paradigm and ...
Alejandro Javier García
doaj  

Home - About - Disclaimer - Privacy