Results 61 to 70 of about 383,659 (283)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Use of Reactive Programming in the Proposed Model for Cloud Security Controlled by ITSS
Computers, 2022 Reactive programming is a popular paradigm that has been used as a new solution in our proposed model for security in the cloud. In this context, we have been able to reduce the execution time compared to our previous work for the model proposed in cloud
Dhuratë Hyseni +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A multi-paradigm approach for mobile agents development
Journal of Computer Science and Technology, 2001 Mobile agent systems have received important attention in the last years as a new programming paradigm for widely distributed and heterogeneous systems.
Edgardo A. Belloni
doaj
Graphical Flow-based Spark Programming
Journal of Big Data, 2020 Increased sensing data in the context of the Internet of Things (IoT) necessitates data analytics. It is challenging to write applications for Big Data systems due to complex, highly parallel software frameworks and systems.
Tanmaya Mahapatra, Christian Prehofer
doaj +1 more source
Alternation in Quantum Programming: From Superposition of Data to Superposition of Programs [PDF]
, 2014 We extract a novel quantum programming paradigm - superposition of programs - from the design idea of a popular class of quantum algorithms, namely quantum walk-based algorithms.
Feng, Yuan, Ying, Mingsheng, Yu, Nengkun
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
A Visual Programming Paradigm for Abstract Deep Learning Model Development
, 2019 Deep learning is one of the fastest growing technologies in computer science with a plethora of applications. But this unprecedented growth has so far been limited to the consumption of deep learning experts.
Aralikatte, Rahul +5 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Reachability under Contextual Locking [PDF]
Logical Methods in Computer Science, 2013 The pairwise reachability problem for a multi-threaded program asks, given control locations in two threads, whether they can be simultaneously reached in an execution of the program.
Remi Bonnet +3 more
doaj +1 more source