Results 41 to 50 of about 383,659 (283)

Maternal Low-Protein Diet During Nursing Leads to Glucose–Insulin Dyshomeostasis and Pancreatic-Islet Dysfunction by Disrupting Glucocorticoid Responsiveness in Male Rats

open access: yesBiology
Both perinatal malnutrition and elevated glucocorticoids are pivotal triggers of the growing global pandemic of metabolic diseases. Here, we studied the effects of metabolic stress responsiveness on glucose–insulin homeostasis and pancreatic-islet ...
Paulo Cezar de Freitas Mathias   +11 more
doaj   +1 more source

Kickstarting Choreographic Programming

open access: yes, 2015
We present an overview of some recent efforts aimed at the development of Choreographic Programming, a programming paradigm for the production of concurrent software that is guaranteed to be correct by construction from global descriptions of ...
Montesi, Fabrizio
core   +1 more source

Confessions of a live coder [PDF]

open access: yes, 2011
This paper describes the process involved when a live coder decides to learn a new musical programming language of another paradigm. The paper introduces the problems of running comparative experiments, or user studies, within the field of live coding ...
Magnusson, Thor
core   +3 more sources

A Statecharts-Based Approach for WSN Application Development

open access: yesJournal of Sensor and Actuator Networks, 2020
Wireless Sensor Network (WSN) software development challenges developers in two main ways: through system programming, which requires expertise in hardware and network management; and application programming, which requires domain-specific knowledge ...
Ismo Hakala, Xinyu Tan
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Replicode: A Constructivist Programming Paradigm and Language [PDF]

open access: yes, 2013
Replicode is a language designed to encode short parallel programs and executable models, and is centered on the notions of extensive pattern-matching and dynamic code production.
Nivel, Eric, Thórisson, Kristinn R.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Low-Code Mixed Reality Programming Framework for Collaborative Robots: From Operator Intent to Executable Trajectories

open access: yesRobotics
Efficient and intuitive programming strategies are essential for enabling robots to adapt to small-batch, high-mix production scenarios. Mixed reality (MR) and programming by demonstration (PbD) have shown great potential to lower the programming barrier
Ziyang Wang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy