Results 41 to 50 of about 6,611,777 (348)

Maternal Low-Protein Diet During Nursing Leads to Glucose–Insulin Dyshomeostasis and Pancreatic-Islet Dysfunction by Disrupting Glucocorticoid Responsiveness in Male Rats

open access: yesBiology
Both perinatal malnutrition and elevated glucocorticoids are pivotal triggers of the growing global pandemic of metabolic diseases. Here, we studied the effects of metabolic stress responsiveness on glucose–insulin homeostasis and pancreatic-islet ...
Paulo Cezar de Freitas Mathias   +11 more
doaj   +1 more source

An Integer Linear Programming Model for Partially Ordered Sets

open access: yesJournal of Mathematics, 2022
Linear programming is an important approach that is used to represent a large class of combinatorial optimization problems. The simplex algorithm is one of the algorithms for solving linear programming problems with exponential time complexity ...
Elsayed Badr   +3 more
doaj   +1 more source

Differentiable Programming Tensor Networks [PDF]

open access: yesPhysical Review X, 2019
Differentiable programming is a fresh programming paradigm which composes parameterized algorithmic components and trains them using automatic differentiation (AD).
H. Liao, Jin-Guo Liu, Lei Wang, T. Xiang
semanticscholar   +1 more source

Society-in-the-loop: programming the algorithmic social contract [PDF]

open access: yesEthics and Information Technology, 2017
Recent rapid advances in Artificial Intelligence (AI) and Machine Learning have raised many questions about the regulatory and governance mechanisms for autonomous machines.
Iyad Rahwan
semanticscholar   +1 more source

Polymorphic Types in ACL2 [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
This paper describes a tool suite for the ACL2 programming language which incorporates certain ideas from the Hindley-Milner paradigm of functional programming (as exemplified in popular languages like ML and Haskell), including a "typed" style of ...
Benjamin Selfridge, Eric Smith
doaj   +1 more source

A Statecharts-Based Approach for WSN Application Development

open access: yesJournal of Sensor and Actuator Networks, 2020
Wireless Sensor Network (WSN) software development challenges developers in two main ways: through system programming, which requires expertise in hardware and network management; and application programming, which requires domain-specific knowledge ...
Ismo Hakala, Xinyu Tan
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Foundations of Total Functional Data-Flow Programming [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2014
The field of declarative stream programming (discrete time, clocked synchronous, modular, data-centric) is divided between the data-flow graph paradigm favored by domain experts, and the functional reactive paradigm favored by academics.
Baltasar Trancón y Widemann   +1 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

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