Results 41 to 50 of about 381,028 (332)
ScaFi: A Scala DSL and Toolkit for Aggregate Programming
SoftwareX, 2022 Supported by current socio-scientific trends, programming the global behaviour of whole computational collectives makes for great opportunities, but also significant challenges.
Roberto Casadei +3 more
doaj +1 more source
A Visual Programming Paradigm for Abstract Deep Learning Model Development
, 2019 Deep learning is one of the fastest growing technologies in computer science with a plethora of applications. But this unprecedented growth has so far been limited to the consumption of deep learning experts.
Aralikatte, Rahul +5 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Use of Reactive Programming in the Proposed Model for Cloud Security Controlled by ITSS
Computers, 2022 Reactive programming is a popular paradigm that has been used as a new solution in our proposed model for security in the cloud. In this context, we have been able to reduce the execution time compared to our previous work for the model proposed in cloud
Dhuratë Hyseni +3 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Kickstarting Choreographic Programming
, 2015 We present an overview of some recent efforts aimed at the development of Choreographic Programming, a programming paradigm for the production of concurrent software that is guaranteed to be correct by construction from global descriptions of ...
Montesi, Fabrizio
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
A multi-paradigm approach for mobile agents development
Journal of Computer Science and Technology, 2001 Mobile agent systems have received important attention in the last years as a new programming paradigm for widely distributed and heterogeneous systems.
Edgardo A. Belloni
doaj
The paradigms of programming [PDF]
Communications of the ACM, 1979 Today I want to talk about the paradigms of programming, how they affect our success as designers of computer programs, how they should be taught, and how they should be embodied in our programming languages.
openaire +2 more sources