Results 151 to 160 of about 1,254,012 (356)

RBTT-04. DOES EXERCISE IMPROVE PROGRESSION FREE SURVIVAL AND QUALITY OF LIFE IN PATIENTS WITH GLIOBLASTOMA? A TRIAL IN PROGRESS [PDF]

, 2018
Kim Edelstein, Kristin L. Campbell, Lori J. Bernstein, Ilyse Lax, Felicity Backhouse, Gregory R. Pond, Navya Kalidindi, Rosemarylin Or, Normand Laperrière, Barbara‐Ann Millar, David Shultz, Alejandro Berlín, Gelareh Zadeh, Catherine Maurice, Warren Mason   +14 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Association of Lung Immune Prognostic Index (LIPI) with Disease Control Rate and Progression-Free Survival in Patients with Soft-Tissue Sarcoma Treated with Immunotherapy in Early-Phase Trials [PDF]

Marianne Zoghbi, Bharti Patel, Matthieu Roulleaux Dugage, Laura Mezquita, Rastilav Bahleda, Armelle Dufresne, Mehdi Brahmi, Isabelle Ray‐Coquard, Patricia Pautier, Jean‐Yves Blay, Axel Le Cesne, Christophe Massard, Benjamin Besse, Édouard Auclin, Elise F. Nassif   +14 more
openalex   +1 more source

Validating radiographic progression-free survival [PDF]

Nature Reviews Urology, 2018
openaire   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Extended Survival and Prognostic Factors in Endometrial Cancer: A Multivariate Cox Regression Analysis

Clinical and Experimental Obstetrics & Gynecology
Background: Endometrial cancer (EC) is the third most prevalent neoplasm among women in Spain and the most frequent malignancy of the female genital tract. The primary risk factors are associated with increased estrogen levels.
Irene Valencia Téllez, Laura De Pablo Zamora, María Castillo Lara, Claudia Vivas Flores, Carlos Vega Reina, Juan Jesús Fernández Alba   +5 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Clinicopathologic significance of heat shock protein 60 as a survival predictor in breast carcinoma

Frontiers in Oncology
BackgroundWhile Heat Shock Protein 60 (HSP60) has been linked to human tumor, its clinic significance specifically in breast carcinoma is unclear. This investigation aims to retrospectively evaluate how HSP60 protein levels relate to survival outcomes ...
Qing Wang, Shengzhou Chen, Zhihong Wu, Jungang Ni   +3 more
doaj   +1 more source

Functional and symptom impact of trametinib versus chemotherapy in BRAF V600E advanced or metastatic melanoma: quality-of-life analyses of the METRIC study [PDF]

, 2017
We report the first quality-of-life assessment of a MEK inhibitor in metastatic melanoma from a phase III study. Trametinib prolonged progression-free survival and improved overall survival versus chemotherapy in patients with BRAF V600 mutation-positive
Amonkar, M. M., Casey, M., Demidov, L. V., Dummer, R., Garbe, C., Grotzinger, K., Hassel, J. C., Lefeuvre-Plesse, C., Milhem, M., Mohr, P., Patel, K., Robert, C., Rutkowski, P., Rutten, A., Schadendorf, D., Sherman, L., Steven, N., Trefzer, U., Ullenhag, G., Wolter, P., Wu, F. S.   +20 more
core  

ACTR-45. FATTY ACID SYNTHASE INHIBITOR TVB-2640 INCREASES PROGRESSION FREE SURVIVAL IN RECURRENT GBM [PDF]

, 2019
Brandon Konkel, Joel Michalek, Enrique Diaz Duque, Qiangia Liu, Laura Caflisch, Vinu Madhu, Andrew Brenner   +6 more
openalex   +1 more source