Results 61 to 70 of about 82,833 (333)

The Modern Value of Clinical Autopsies

open access: yesActa Médica Portuguesa, 2015
Keywords: Autopsy; Antiretroviral Therapy, Highly Active; HIV Infections; Leukoencephalopathy, Progressive Multifocal.
Carlos Marques Pontinha
doaj   +1 more source

A Case of Progressive Multifocal Leucoencephalopathy and Cerebral Toxoplasmosis in an HIV-Infected Patient

open access: yesActa Medica Bulgarica, 2023
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the central nervous system (CNS) caused by the reactivation of John Cunningham polyomavirus (JCV).
Yancheva-Petrova N.   +6 more
doaj   +1 more source

Immunological biomarkers identifying natalizumab-treated multiple sclerosis patients at risk of progressive multifocal leukoencephalopathy [PDF]

open access: yes, 2014
Natalizumab-induced progressive multifocal leukoencephalopathy (PML) appears to be unleashed by complex interactions between viral and immunological host factors leading the latent form of JC virus to become pathogenic.
A.SOTTINI   +8 more
core   +1 more source

JC virus-induced progressive multifocal leukoencephalopathy in a presumably healthy patient

open access: yesBMC Neurology, 2022
Background JC virus (JCV) is common among healthy individuals and remains latent but may be reactivated under immunosuppressive conditions, resulting in progressive multifocal leukoencephalopathy (PML).
Xiang Wang   +4 more
doaj   +1 more source

Progressive multifocal leukoencephalopathy associated with chemotherapy induced lymphocytopenia in solid tumors – case report of an underestimated complication [PDF]

open access: yes, 2022
Background JC virus reactivation causing progressive multifocal leukoencephalopathy (PML) occurs preferentially in human immunodeficiency virus (HIV) positive individuals or patients suffering from hematologic neoplasms due to impaired viral control ...
Claus, Rainer   +7 more
core   +1 more source

Rituximab-Associated Inflammatory Progressive Multifocal Leukoencephalopathy

open access: yesCase Reports in Infectious Diseases, 2016
Progressive multifocal leukoencephalopathy (PML) is a rare disease of the immunosuppression that results from neurotropic invasion of the JC virus which leads to demyelination of oligodendrocytes.
Chandra Punch   +2 more
doaj   +1 more source

Multifocal Stereoscopic Projection Mapping [PDF]

open access: yes, 2021
Stereoscopic projection mapping (PM) allows a user to see a three-dimensional (3D) computer-generated (CG) object floating over physical surfaces of arbitrary shapes around us using projected imagery. However, the current stereoscopic PM technology only satisfies binocular cues and is not capable of providing correct focus cues, which causes a vergence-
arxiv   +1 more source

Killing Two Birds With One Stone: Effective Control of Both Non-Small Cell Lung Cancer and Progressive Multifocal Leukoencephalopathy With Atezolizumab, A Case Report

open access: yesFrontiers in Immunology, 2022
Treating patients with cancer complicated by severe opportunistic infections is particularly challenging since classical cancer treatments, such as chemotherapy, often induce profound immune suppression and, as a result, may favor infection progression ...
Nicolas Lambert   +11 more
doaj   +1 more source

Pharmacokinetic Model‐Informed Precision Dosing of Natalizumab in Multiple Sclerosis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Intravenous natalizumab is an effective treatment for relapsing–remitting multiple sclerosis. However, the standard treatment interval of 4 weeks may be excessive for many patients. Personalized interval extension using therapeutic drug monitoring (TDM) can result in adequate drug exposure while reducing hospital visits and healthcare costs ...
Stefan P. H. van den Berg   +9 more
wiley   +1 more source

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