Results 71 to 80 of about 82,833 (333)
A 58-year-old woman with a history of systemic lupus erythematosus (SLE) who was taking prednisolone and mycophenolate mofetil presented with gait disturbances that progressively worsened over a period of 3 months. Her blood test and cerebrospinal fluid (
Takayoshi Akimoto+4 more
doaj +1 more source
Frequent Infection of Cerebellar Granule Cell Neurons by Polyomavirus JC in Progressive Multifocal Leukoencephalopathy [PDF]
Progressive multifocal leukoencephalopathy (PML) occurs most often in immunosuppressed individuals. The lesions of PML result from astrocyte and oligodendrocyte infection by the polyomavirus JC (JCV); JCV has also been shown to infect and destroy ...
Beckwith, Curt+7 more
core +1 more source
Importance Risk of developing progressive multifocal leukoencephalopathy (PML) is the major barrier to using natalizumab for patients with multiple sclerosis (MS). To date, the association of risk stratification with PML incidence has not been evaluated.
S. Vukusic+39 more
semanticscholar +1 more source
Detection of Vascular Leukoencephalopathy in CT Images [PDF]
Artificial intelligence (AI) has seen a significant surge in popularity, particularly in its application to medicine. This study explores AI's role in diagnosing leukoencephalopathy, a small vessel disease of the brain, and a leading cause of vascular dementia and hemorrhagic strokes.
arxiv +1 more source
Metastatic Cancer Outcome Prediction with Injective Multiple Instance Pooling [PDF]
Cancer stage is a large determinant of patient prognosis and management in many cancer types, and is often assessed using medical imaging modalities, such as CT and MRI. These medical images contain rich information that can be explored to stratify patients within each stage group to further improve prognostic algorithms.
arxiv
JCV-specific T-cells producing IFN-gamma are differently associated with PmL occurrence in HIV patients and liver transplant recipients [PDF]
Aim of this work was to investigate a possible correlation between the frequency of JCV-specific T-cells and PML occurrence in HIV-infected subjects and in liver transplant recipients.
Agrati, C+14 more
core
Brain abscess following rituximab infusion in a patient with pemphigus vulgaris. [PDF]
BackgroundImmunocompromised patients are at increased risk for developing meningitis or, rarely, brain abscess with opportunistic organisms like Listeria monocytogenes.Case reportA 52 year-old Saudi Arabian woman who was diagnosed with pemphigus vulgaris
Al-Harbi, Talal M+2 more
core +2 more sources
From Clinical Presentation to the Outcome: the Natural History of PML in a Portuguese Population of HIV Infected Patients [PDF]
Background Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system, associated with immunosuppression states.
Almeida, I.+3 more
core +2 more sources
Summary Developing new therapeutic regimens for relapsed/refractory (R/R) B non‐Hodgkin lymphoma (NHL) patients remains a significant unmet clinical need. Our objective was to evaluate atezolizumab (ATE), obinutuzumab (OBI) and venetoclax (VEN) combination in patients with R/R NHL who had received at least one prior anti‐CD20‐containing ...
Charles Herbaux+21 more
wiley +1 more source
Abstract Objectives This retrospective, observational, non‐interventional study describes the demographics, characteristics, immunological and virological status, coinfections, healthcare unit of HIV diagnosis and follow‐up status of Ukrainian refugees with newly diagnosed HIV in the Czech Republic, with a special focus on those with a late HIV ...
Zofia Bartovská+20 more
wiley +1 more source