Results 161 to 170 of about 8,307 (217)

Cortical lesions are common in a longitudinal progressive multifocal leukoencephalopathy cohort. [PDF]

open access: yesBrain Commun
Walvekar S   +10 more
europepmc   +1 more source

The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases

Journal of Autoimmunity, 2008
Progressive multifocal leukoencephalopathy (PML) is a rare and devastating neurological disease with areas of demyelination in the central nervous system classically associated with profound imunosuppression. PML is caused by reactivation of latent JC virus, leading to the death of myelin-producing oligodendrocytes typically with a rapidly fatal ...
Aftab Ahmed Ansari
exaly   +3 more sources

Progressive Multifocal Leukoencephalopathy (PML)

2014
Progressive multifocal leukoencephalopathy (PML) was first considered a distinct neurological entity in 1958. Its neuropathology is represented by multifocal demyelinating lesions accompanying oligodendroglia-like cells with markedly enlarged nuclei. Electron microscopy in 1965 showed polyomavirus-like structures in the enlarged nuclei.
exaly   +2 more sources

Spontaneous progressive multifocal leukoencephalopathy (PML) in macaques

Nature, 1975
PROGRESSIVE multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) which has so far been recognised only in man1,2. Although it is an infrequent cause of clinical neurological disorder3, it is of particular interest because of its frequent association with diseases in which immunological competence is ...
D H, Gribble   +3 more
openaire   +2 more sources

Are astrocytes infected in progressive multifocal leukoencephalopathy (PML)?

Acta Neuropathologica, 1982
Ultrastructural characteristics of the early steps of PML virus infection, i.e. adsorption, penetration, and intracellular virus transport were demonstrated in astrocytes. These phenomena were more frequently seen in the cytoplasm than virus assembly in the nuclei. Infection of the astrocytes is usually non-productive.
M, Mázló, I, Tariska
openaire   +2 more sources

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