Results 81 to 90 of about 33,332 (299)
Pilot Study of [11C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer
CellsA novel brain positron emission tomography (PET) radioligand, [11C]HY-2-15, has potential for imaging alpha-synuclein aggregations in multiple system atrophy and misfolded tau proteins in tauopathies, based on its high binding affinity in disease brain ...
Chia-Ju Hsieh +11 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Compared to Parkinson's disease, atypical parkinsonian disorders (APD) are characterized by a more rapidly progressive course, often leading to profound disability. Effective communication between clinicians, patients, and care partners is essential to support patient‐centered care and shared decision‐making.
Michiko K. Bruno +7 more
wiley +1 more source
Behavioral and Neurophysiological Effects of Transdermal Rotigotine in Atypical Parkinsonism [PDF]
, 2014 Effective therapies for the so-called atypical parkinsonian syndrome (APS) such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), or corticobasal syndrome (CBS) are not available.
Davide Vito Moretti +3 more
core +2 more sources
An Exploration of the High Prevalence of Parkinson's Disease in a Rural Area of North West England
Movement Disorders Clinical Practice, EarlyView.Abstract Background Globally the prevalence of Idiopathic Parkinson's Disease (IPD) is rising. Increasing recognition is being given to the influence of environmental factors on this rise, although the precise impact of such factors remains poorly understood.
Rosanna Varden +2 more
wiley +1 more source
Corticobasal degeneration and corticobasal syndrome: A review
Clinical Parkinsonism & Related Disorders, 2019 Corticobasal degeneration (CBD) is a rare neurodegenerative disorder. The most common presentation of CBD is the corticobasal syndrome (CBS), which is a constellation of cortical and extrapyramidal symptoms and signs.
Vasilios C. Constantinides +4 more
doaj +1 more source
A Case of Multiple Sclerosis Presenting as Eight and Half Syndrome. [PDF]
, 2013 Multiple sclerosis (MS) is a chronic disease characterized by inflammation, demyelination, gliosis (scarring), and neuronal loss; the course can be relapsing-remitting or progressive.
Kaushik, M +4 more
core
The binaural masking level difference: cortical correlates persist despite severe brain stem atrophy in progressive supranuclear palsy. [PDF]
, 2014 Under binaural listening conditions, the detection of target signals within background masking noise is substantially improved when the interaural phase of the target differs from that of the masker.
Carlyon, Robert P +5 more
core +3 more sources
Movement Disorders Clinical Practice, EarlyView.Abstract Background Findings are contradictory regarding changes in the incidence and prevalence of Parkinson's disease (PD) over time; data for other parkinsonian disorders are rare. Objectives To analyze temporal trends in the incidence and prevalence of eight parkinsonisms (PD, MSA, PSP, CBS, DLB, vascular parkinsonism, drug‐induced parkinsonism ...
Sacha E. Gandhi +7 more
wiley +1 more source
Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum [PDF]
, 2005 In contrast to the common and genetically complex senile form of Alzheimer's disease (AD), the molecular genetic dissection of inherited presenile dementias has given important mechanistic insights into the pathogenesis of degenerative brain disease ...
Cruts, Marc +5 more
core +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background and objectives Caregivers of progressive supranuclear palsy (PSP) patients frequently show significant distress. The Parkinsonism Carers quality of life (QoL) (PQoL Carer) is a valid tool evaluating the effect of PSP on caregivers' QoL.
Arianna Cappiello +73 more
wiley +1 more source