Attenuated lamin A-prohibitin2 interaction leads to mitochondrial dysfunction in LMNA 289 A>G-mediated dilated cardiomyopathy. [PDF]
Nath S +4 more
europepmc +1 more source
Development of capsaicin-derived prohibitin ligands to modulate the Aurora kinase A/PHB2 interaction and mitophagy in cancer cells. [PDF]
Djehal A +7 more
europepmc +1 more source
The role of natural compounds in modulation of small extracellular vesicle biogenesis and lipid metabolism in cancer. [PDF]
Lim GY +3 more
europepmc +1 more source
UBC9-Mediated SUMO Pathway Drives Prohibitin-1 Nuclear Accumulation and PITX1 Repression in Primary Osteoarthritis. [PDF]
Doucet R +12 more
europepmc +1 more source
From isolation to insights: mitochondrial complex I in the diatom Phaeodactylum tricornutum. [PDF]
Berdun F +7 more
europepmc +1 more source
LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis. [PDF]
Li H, Song M, Hylemon PB, Zhou H.
europepmc +1 more source
Mitochondria and the epigenome: maternal co-inheritance and crosstalk from oocyte to embryo. [PDF]
Lee SH, Cui XS.
europepmc +1 more source
Prohibitin, an antiproliferative protein, is localized to mitochondria
Prohibitin is a ubiquitously expressed protein with antiproliferative properties. When rat prohibitin tagged with a carboxy‐terminal c‐Myc epitope was expressed in baby hamster kidney cells the protein was targeted to mitochondria. In immunofluorescence microscopy prohibitin colocalized with a mitochondrial marker E3. Immunoelectron microscopy revealed
Elina Ikonen +2 more
exaly +7 more sources
Prohibitin 1 in liver injury and cancer [PDF]
Prohibitin 1 is an evolutionary conserved and ubiquitously expressed protein that exerts different biological functions depending on its subcellular localization. The role of prohibitin 1 in liver cancer is controversial as it can be pro- or anti-tumorigenic.
Lucia Barbier-Torres, Shelly C Lu
exaly +7 more sources
Unveiling the potential of prohibitin in cancer [PDF]
Recently, research has shed new light on the role of Prohibitin (PHB) in cancer pathogenesis across an array of cancer types. Important mechanisms for PHB have been unveiled in several cancers, especially with regard to the androgen independent state of prostate cancer (PC) and oestrogen dependent breast cancer.
Wen G Jiang, D Alwyn Dart
exaly +3 more sources

