Results 181 to 190 of about 11,777 (218)

Dual-Targeted Glucose-Dependent Insulinotropic Polypeptide-Loaded Photothermal Nanoparticles to Prevent Obesity via Lipolysis and Browning of White Adipose Tissue. [PDF]

Small Sci
Xie T, Zhao L, Pei S, Wen K, Fei S, Chen W, Li Z, Zhang L, Li L, Guo L, Huang H, Pan Q.   +11 more
europepmc   +1 more source

IGFBP6 orchestrates antiinfective immune collapse in murine sepsis via prohibitin-2-mediated immunosuppression. [PDF]

J Clin Invest
Chen K, Hu Y, Yu X, Tang H, Ruan Y, Li Y, Gao X, Zhao Q, Wang H, Zhang X, Molloy DP, Yin Y, Chen D, Song Z.   +13 more
europepmc   +1 more source

The Host Immune Response to Enterovirus A71 (EV-A71): From Viral Immune Evasion to Immunopathology and Prognostic Biomarkers of Severe Disease-A Narrative Review. [PDF]

Viruses
Andronik A, Lewandowski D, Sulik A, Toczylowski K.   +3 more
europepmc   +1 more source

CK2α Overexpression in Colorectal Cancer: Evidence for Sex- and Age-Linked Differences. [PDF]

Cancers (Basel)
Friedrich JR, Meier C, Plotz G, Zeuzem S, Brieger A, Overby SJ.   +5 more
europepmc   +1 more source

Androgens target prohibitin to regulate proliferation of prostate cancer cells [PDF]

Oncogene, 2004
Eric W-F Lam, Charlotte Bevan
exaly   +3 more sources

Prohibitin 1 in liver injury and cancer

Experimental Biology and Medicine, 2020
Prohibitin 1 is an evolutionary conserved and ubiquitously expressed protein that exerts different biological functions depending on its subcellular localization. The role of prohibitin 1 in liver cancer is controversial as it can be pro- or anti-tumorigenic.
Lucía Barbier-Torres, Shelly C Lu
exaly   +6 more sources

Unveiling the potential of prohibitin in cancer [PDF]

Cancer Letters, 2015
Recently, research has shed new light on the role of Prohibitin (PHB) in cancer pathogenesis across an array of cancer types. Important mechanisms for PHB have been unveiled in several cancers, especially with regard to the androgen independent state of prostate cancer (PC) and oestrogen dependent breast cancer.
Wen Guo Jiang
exaly   +3 more sources

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Molecular modeling of prohibitin domains

Proteins: Structure, Function, and Bioinformatics, 2007
AbstractProhibitins comprise a family of highly conserved ubiquitous eukaryotic proteins that mainly localize to the mitochondria. They have been implicated in important cellular processes such as cellular signaling and transcriptional control, apoptosis, cellular senescence, and mitochondrial biogenesis.
Winter, Anja, Kamarainen, Outi, Hofmann, Andreas   +2 more
openaire   +3 more sources

Prohibitin and the senescent phenotype

Experimental Gerontology, 1996
Prohibitin is an evolutionarily conserved gene that has antiproliferative activity, is ubiquitously expressed, and appears to be essential for cell survival. The gene codes for a 30 kD, post-synthetically modified protein located primarily in the mitochondria.
R T, Dell'Orco, J K, McClung, E R, Jupe, X T, Liu   +3 more
openaire   +2 more sources

Prohibitin 2: At a communications crossroads

IUBMB Life, 2015
AbstractProhibitins (PHBs) are a highly conserved class of proteins first discovered as inhibitors of cellular proliferation. Since then PHBs have been found to have a significant role in transcription, nuclear signaling, mitochondrial structural integrity, cell division, and cellular membrane metabolism, placing these proteins among the key regulators
Bavelloni A, Piazzi M, Raffini M, Faenza I, Blalock WL   +4 more
openaire   +2 more sources