Results 91 to 100 of about 1,065,082 (380)

IFN-gamma is associated with risk of Schistosoma japonicum infection in China.

, 2003
Before the start of the schistosomiasis transmission season, 129 villagers resident on a Schistosoma japonicum-endemic island in Poyang Lake, Jiangxi Province, 64 of whom were stool-positive for S.
Bickle, QD, Chen, SZ, Cousens, SN, Hu, LS, Ji, MJ, Shen, L, Su, C, Taylor, MG, Weir, RE, Wu, GL, Wu, HW, Xie, ZW, Zhang, Y, Zhang, ZS   +13 more
core   +1 more source

Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses [PDF]

The Journal of Immunology, 2012
Abstract Neutrophils (polymorphonuclear neutrophils [PMNs]) play an elaborate role in the innate immune response against invading pathogens. Recent research provided evidence that PMNs can play a modulatory role in inflammation next to their primary role of phagocytosis.
Gresnigt, M.S., Joosten, L.A.B., Verschueren, I., Meer, J.W.M. van der, Netea, M.G., Dinarello, C.A., van de Veerdonk, F.L.   +6 more
openaire   +3 more sources

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins

Molecular Biology of the Cell, 2014
Epithelial barriers are vital components of the innate immune system. This barrier is provided by tight junctions and compromised by proinflammatory cytokine signaling.
Christopher T. Capaldo, A. Farkas, R. Hilgarth, S. Krug, Mattie F. Wolf, Jeremy K. Benedik, M. Fromm, Michael Koval, C. Parkos, A. Nusrat   +9 more
semanticscholar   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Considerations for Defining Cytokine Dose, Duration, and Milieu That Are Appropriate for Modeling Chronic Low-Grade Inflammation in Type 2 Diabetes

Journal of Diabetes Research, 2016
Proinflammatory cytokines have been implicated in the pathophysiology of both type 1 diabetes (T1D) and type 2 diabetes (T2D). T1D is an autoimmune disease involving the adaptive immune system responding to pancreatic beta-cells as antigen-presenting ...
Craig S. Nunemaker
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Palmitate and insulin synergistically induce IL-6 expression in human monocytes

Cardiovascular Diabetology, 2010
Background Insulin resistance is associated with a proinflammatory state that promotes the development of complications such as type 2 diabetes mellitus (T2DM) and atherosclerosis.
Lumpkin Charles K, Thrailkill Kathryn M, Ou Yang, Cockrell Gael E, Bunn Robert C, Fowlkes John L   +5 more
doaj   +1 more source

Anti‐inflammatory activity of arctigenin against PCV2 infection in a mouse model

Veterinary Medicine and Science, 2022
Arctigenin (ACT) is a novel anti‐inflammatory lignan extracted from Arctium lappa L, a herb commonly used in traditional Chinese herbal medicine.
Lijun Wu, Jie Chen, Danna Zhou, Runshan Chen, Xiabing Chen, Zhiyong Shao, Wenhai Yang, Bin He   +7 more
doaj   +1 more source

Differences in Inflammatory Markers between Nulliparous Women Admitted to Hospitals in Preactive vs Active Labor [PDF]

, 2015
Objective To determine whether labor-associated inflammatory markers differ between low-risk, nulliparous women in preactive vs active labor at hospital admission and over time.
Arntzen, Bailit, Banchereau, Bennett, Bennett, Bollapragada, Caughey, Donna O. McCarthy, Golightly, Gotsch, Greig, Gucer, Hamilton, Hebisch, Holm, Holmes, Impey, Jane M. Lamp, Jarocki, Jeremy L. Neal, Kumar, Lin, Loraine T. Sinnott, Mikolajczyk, Mitchell, Nancy K. Lowe, Neal, Neal, Norman, Nowak, Nowak, Opsjln, Osman, Osmers, Papatheodorou, Ragusa, Rahnama, Roh, Romero, Sennstrom, Shannon L. Gillespie, Shynlova, Thomson, Torbe, Tribe, Vitoratos, Vitoratos, Young, Yuan, Zhang, Zhang   +50 more
core   +2 more sources

Chemically Modified N-Acylated Hyaluronan Fragments Modulate Proinflammatory Cytokine Production by Stimulated Human Macrophages*

Journal of Biological Chemistry, 2014
Background: Low molecular mass hyaluronan (LMHA) is proinflammatory, but the role of the N-acetyl moieties is unknown. Results: Chemical reacetylation of LMHA results in maximal proinflammatory cytokine production by human macrophages, compared with ...
Oladunni Babasola, K. Rees-Milton, Siziwe Bebe, Jiaxi Wang, T. Anastassiades   +4 more
semanticscholar   +1 more source