Results 111 to 120 of about 1,021,035 (396)

The effect of the treatment of denture related stomatitis on peripheral T cells and monocytes [PDF]

, 2017
Purpose: Systemic immune activation has been recently linked to chronic inflammatory disorders of the oral cavity, particularly to periodontitis. The purpose of this study was to determine whether treatment of a fungus-induced oral inflammation, namely ...
Czesnikiewicz-Guzik, Marta, Maciag, Anna, Maciag, Joanna, Matusik, Pawel, Mikolajczyk, Tomasz, Nowakowski, Daniel, Osmenda, Grzegorz, Robertson, Douglas   +7 more
core   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Influence of proinflammatory cytokine gene polymorphism on childhood obesity

European Journal of Medical Research, 2009
Background Obesity development is a complex process which can be influenced by genetic predisposition modified by environmental factors. Nowadays, the problem of overweight and obesity, including related complications, occurs in increasingly younger ...
Popko K, Górska E, Pyrzak B, Telmaszczyk-Emmel A, Wisniewska A, Majcher A, Wasik M, Demkow U   +7 more
doaj   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk [PDF]

, 2011
<p><b>Objective:</b> The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD).</p> <p><b>Methods and Results:</b> In the ...
Craen, A.J.M. de, Ford, I., Jukema, J.W., McInnes, I.B., Murray, H.M., Packard, C.J., PROSPER Study Grp, Sattar, N., Stott, D.J., Trompet, S., Welsh, P., Westendorp, R.G.J.   +11 more
core   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

Journal of Neuroinflammation, 2008
Background Cytokines and alcohol share a common modulation of inflammation and hormones as well as being implicated in multiple diseases, but the mechanisms are poorly understood.
Hong Jau-Shyong, Pluzarev Olivera, Hanes Richard N, He Jun, Qin Liya, Crews Fulton T   +5 more
doaj   +1 more source

Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

Journal of Experimental Medicine, 2012
HMGB1 orchestrates leukocyte recruitment and their induction to secrete inflammatory cytokines by switching between mutually exclusive redox states.
E. Vénéreau, Maura Casalgrandi, M. Schiraldi, D. Antoine, A. Cattaneo, F. De Marchis, J. Liu, A. Antonelli, A. Preti, L. Raeli, S. Shams, Huan Yang, L. Varani, U. Andersson, K. Tracey, A. Bachi, M. Uguccioni, M. Bianchi   +17 more
semanticscholar   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source