Results 11 to 20 of about 1,065,082 (380)

Complement Receptor-Mediated Phagocytosis Induces Proinflammatory Cytokine Production in Murine Macrophages

open access: yesFrontiers in Immunology, 2020
Macrophages are professional phagocytes that are uniquely situated between the innate and adaptive arms of immunity with a high capacity for phagocytosis and proinflammatory cytokine production as well as antigen presentation.
Durga Acharya   +3 more
doaj   +2 more sources

Granzymes Regulate Proinflammatory Cytokine Responses [PDF]

open access: yesThe Journal of Immunology, 2015
Abstract Granzymes (Grs) are serine proteases mainly produced by cytotoxic lymphocytes and are traditionally considered to cause apoptosis in tumor cells and virally infected cells. However, the cytotoxicity of several Grs is currently being debated, and additional, predominantly extracellular, functions of Grs in inflammation are ...
Wensink, Annette C.   +2 more
openaire   +4 more sources

Approaching Inflammation Paradoxes—Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

open access: yesFrontiers in Immunology, 2020
The mechanisms that underlie various inflammation paradoxes, metabolically healthy obesity, and increased inflammations after inflammatory cytokine blockades and deficiencies remain poorly determined.
Ming Liu   +25 more
doaj   +2 more sources

Proinflammatory and anti-inflammatory cytokine changes related to menopause

open access: yesMenopause Review, 2014
The aim of the study was to determine menopause-related changes in serum levels of main proinflammatory and anti-inflammatory cytokines. Material and methods: The study included 175 women, who were divided into 5 study groups (group 1 – fertile ...
Andrei Mihai Malutan   +3 more
doaj   +2 more sources

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction [PDF]

open access: bronzeGut, 2017
Shiran Gerassy-Vainberg   +13 more
openalex   +2 more sources

Activation of NF-κB and induction of proinflammatory cytokine expressions mediated by ORF7a protein of SARS-CoV-2

open access: yesScientific Reports, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent for coronavirus disease 2019 (COVID-19) that emerged in human populations recently. Severely ill COVID-19 patients exhibit the elevation of proinflammatory cytokines, and
Chia-Ming Su, Leyi Wang, D. Yoo
semanticscholar   +1 more source

Glycyrrhizin Inhibits PEDV Infection and Proinflammatory Cytokine Secretion via the HMGB1/TLR4-MAPK p38 Pathway

open access: yesInternational Journal of Molecular Sciences, 2020
Our previous study showed that glycyrrhizin (GLY) inhibited porcine epidemic diarrhea virus (PEDV) infection, but the mechanisms of GLY anti-PEDV action remain unclear.
Ruyi Gao   +6 more
semanticscholar   +1 more source

Cytokine Signature in Schnitzler Syndrome: Proinflammatory Cytokine Production Associated to Th Suppression

open access: yesFrontiers in Immunology, 2020
BackgroundSchnitzler syndrome (SchS) is a rare autoinflammatory disease characterized by urticarial exanthema, bone and joint alterations, fever and monoclonal IgM gammopathy.
Marie Masson Regnault   +29 more
doaj   +1 more source

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

open access: yesNature Communications, 2016
Nrf2 (NF-E2-related factor-2) transcription factor regulates oxidative/xenobiotic stress response and also represses inflammation. However, the mechanisms how Nrf2 alleviates inflammation are still unclear.
E. Kobayashi   +10 more
semanticscholar   +1 more source

PHLDA1 Suppresses TLR4-Triggered Proinflammatory Cytokine Production by Interaction With Tollip

open access: yesFrontiers in Immunology, 2022
Pleckstrin homology-like domain, family A, member 1 (PHLDA1) has been reported to be expressed in many mammalian tissues and cells. However, the functions and exact mechanisms of PHLDA1 remain unclear.
Hui Peng   +13 more
doaj   +1 more source

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